ArticleClinical cardiology2022
Left atrial appendage size is a marker of atrial fibrillation recurrence after radiofrequency catheter ablation in patients with persistent atrial fibrillation.
Article in Clinical cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 5 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 5 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Pooled it
- Freedom from atrial arrhythmia and other clinical outcomes at 5 years and beyond after catheter ablation of atrial fibrillation: a systematic review and meta-analysis.European heart journal. Quality of care & clinical outcomes · 2023Pooled it
- Left Atrial Appendage Volume Predicts Atrial Fibrillation Recurrence after Radiofrequency Catheter Ablation: A Meta-Analysis.Arquivos brasileiros de cardiologia · 2023Pooled it
- Left atrial appendage flow velocity predicts recurrence of atrial fibrillation after catheter ablation: A systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2022Pooled it
- Left atrial appendage function and structure predictors of recurrent atrial fibrillation after catheter ablation: A meta-analysis of observational studies.Frontiers in cardiovascular medicine · 2022Pooled it
- Gender differences in the right atrial appendage and right atrium-related structures in patients with atrial fibrillation and their association with ablation outcomes.International journal of cardiology. Heart & vasculature · 2026Article
- Three-Dimensional Left Atrial Geometry in Atrial Fibrillation: Imaging Biomarkers, Substrate Phenotyping, and Ablation Outcome Prediction.Diagnostics (Basel, Switzerland) · 2026Review
- Left Atrial Appendage Morphology Predicts Atrial Fibrillation Recurrence: The Hidden Risks of Windsock Anatomy.Diagnostics (Basel, Switzerland) · 2025Article
- Risk factors and nomogram prediction model for recurrence after radiofrequency ablation in patients with persistent atrial fibrillation.BMC cardiovascular disorders · 2025Article
- Evaluation of the volume and function of the right atrial appendage using computed tomography.BMC cardiovascular disorders · 2025Article
- Impact of response to electrical cardioversion before catheter ablation for persistent atrial fibrillation: a propensity score-matched analysis.European heart journal open · 2025Article
- Cardiac Magnetic Resonance in the Assessment of Atrial Cardiomyopathy and Pulmonary Vein Isolation Planning for Atrial Fibrillation.Journal of imaging · 2025Review
- Concomitant Mechanical Aspiration and Appendage Closure for Recalcitrant Left Atrial Appendage Thrombi.JAMA cardiology · 2025Article
- Comparative analysis of left atrial size and appendage morphology in paroxysmal and persistent atrial fibrillation patients.Journal of arrhythmia · 2025Article
- Adherence to the CLOSE Protocol and Low Baseline Generator Impedance Are Independent Predictors of Durable Pulmonary Vein Isolation.Journal of clinical medicine · 2024Article
- One-Day Interruption of NOAC Is Associated with Low Risk of Periprocedural Adverse Events during Pulmonary Vein Isolation If Combined with Left Atrial Thrombus Exclusion with Computed Tomography.Life (Basel, Switzerland) · 2024Article
- An effective prediction model based on XGBoost for the 12-month recurrence of AF patients after RFA.BMC cardiovascular disorders · 2023Article
- Association of pericoronary adipose tissue with atrial fibrillation recurrence after ablation based on computed tomographic angiography.Japanese journal of radiology · 2023Article
- Value of Imaging in the Non-Invasive Prediction of Recurrence after Catheter Ablation in Patients with Atrial Fibrillation: An Up-to-Date Review.Reviews in cardiovascular medicine · 2023Review
- Association of quantitative computed tomography-based right atrial appendage and right atrium parameters with postradiofrequency ablation recurrence of atrial fibrillation.Quantitative imaging in medicine and surgery · 2023Article
Corrections and comments
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Authors and funding
18 authors at 3 institutions in 3 countries.
Funding
Abstract
introductionThere are no consistently confirmed predictors of atrial fibrillation (AF) recurrence after catheter ablation. Therefore, we aimed to study whether left atrial appendage volume (LAAV) and function influence the long-term recurrence of AF after catheter ablation, depending on AF type.
methodsAF patients who underwent point-by-point radiofrequency catheter ablation after cardiac computed tomography (CT) were included in this analysis. LAAV and LAA orifice area were measured by CT. Uni- and multivariable Cox proportional hazard regression models were performed to determine the predictors of AF recurrence.
resultsIn total, 561 AF patients (61.9 ± 10.2 years, 34.9% females) were included in the study. Recurrence of AF was detected in 40.8% of the cases (34.6% in patients with paroxysmal and 53.5% in those with persistent AF) with a median recurrence-free time of 22.7 (9.3-43.1) months. Patients with persistent AF had significantly higher body surface area-indexed LAV, LAAV, and LAA orifice area and lower LAA flow velocity, than those with paroxysmal AF. After adjustment left ventricular ejection fraction (LVEF) <50% (HR = 2.17; 95% CI = 1.38-3.43; p < .001) and LAAV (HR = 1.06; 95% CI = 1.01-1.12; p = .029) were independently associated with AF recurrence in persistent AF, while no independent predictors could be identified in paroxysmal AF.
conclusionThe current study demonstrates that beyond left ventricular systolic dysfunction, LAA enlargement is associated with higher rate of AF recurrence after catheter ablation in persistent AF, but not in patients with paroxysmal AF.
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