Evidence map›Paper›PMID 34799860›Full record

ArticleMagnetic resonance in medicine2022

Cerebrospinal fluid-tissue exchange revealed by phase alternate labeling with null recovery MRI.

Anna M Li, Jiadi Xu

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Simultaneous measurement of water transport across the blood-brain and blood-CSF barrier in the human brain with arterial spin labeling MRI.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Article
  2. Article
  3. Review
  4. Quantification of TMagnetic resonance in medicine · 2023
    Article
  5. Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Anna M LiF.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Research Institute, Baltimore, Maryland, USA.
Jiadi XuF.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Research Institute, Baltimore, Maryland, USA.ORCID 0000-0001-9698-5622
Kennedy Krieger Institute · US

Funding

TRD 4: Platforms for multi-modal and multi-scale imaging dataP41EB031771 · NIBIB · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI Hanzhang Lu, Peter CM Van Zijl · 2021 to 2026
$9.9M
MRI based phosphocreatine mapping method to assess patients with peripheral arterial disease.R01HL149742 · NHLBI · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI Michael Schaer, JIadi Xu · 2020 to 2026
$2.5M
Imaging brain glucose uptake by onVDMP MRI in Huntington's DiseaseR21NS118079 · NINDS · JOHNS HOPKINS UNIVERSITY · PI DUAN, WENZHEN, XU, JIADI · 2020 to 2020
$465k
Impaired Cerebral Glucose Uptake in the Brain as an MRI Marker for Alzheimer' s DiseaseR21AG065794 · NIA · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI XU, JIADI · 2020 to 2020
$446k
NHLBI NIH HHS R01 HL149742NIA NIH HHS R21 AG065794NIBIB NIH HHS P41 EB031771NINDS NIH HHS R21 NS118079
6 · The paper itself

Abstract

purposeTo develop phase alternate labeling with null recovery (PALAN) MRI methods for the quantification of the water exchange between cerebrospinal fluid (CSF) and other surrounding tissues in the brain.

methodIn both T

resultsBoth T

conclusionThe PALAN methods are suitable tools to study CSF water exchange across different compartments in the brain.

Indexed as

Diffusion Magnetic Resonance ImagingMagnetic Resonance ImagingBrainCerebral VentriclesCerebrospinal Fluidcerebrospinal and interstitial fluid exchangecerebrospinal fluidCSFEpendymal Layerglymphatic systeminterstitial fluidISFPALANphase alternate labeling with null recovery

Identifiers

PMID34799860
PMCPMC8794537
OpenAlexW3214630789

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.