Evidence map›Paper›PMID 34799837›Full record

SynthesisHepatology international2023

Prevalence and risk factors of erectile dysfunction in patients with liver cirrhosis: a systematic review and meta-analysis.

Hye Jin Yoo, Bora Lee, Eun-Ae Jung, Sang Gyune Kim, Young Seok Kim, Jeong-Ju Yoo

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Hepatology international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Sexual Dysfunction in Patients with Chronic Non-Genital Physical Disease: An Umbrella Review.International journal of environmental research and public health · 2025
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Chronic liver diseases and erectile dysfunction.Frontiers in public health · 2022
    Review
  8. Article
  9. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hye Jin Yoo *Division of Gastroenterology and Hepatology, Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, 170 Jomaru-roWonmi-gu, Bucheon-si, Gyeonggi-do, 14584, Republic of Korea.
Bora Lee *Department of Statistics, Graduate School of Chung-Ang University, Seoul, Republic of Korea.
Eun-Ae JungMedical Library, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.
Sang Gyune KimDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, 170 Jomaru-roWonmi-gu, Bucheon-si, Gyeonggi-do, 14584, Republic of Korea.
Young Seok KimDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, 170 Jomaru-roWonmi-gu, Bucheon-si, Gyeonggi-do, 14584, Republic of Korea.
Jeong-Ju YooDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, 170 Jomaru-roWonmi-gu, Bucheon-si, Gyeonggi-do, 14584, Republic of Korea. puby17@naver.com.ORCID http://orcid.org/0000-0002-7802-0381
Soonchunhyang University · KRChung-Ang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsLiver cirrhosis is associated with an increased risk of developing erectile dysfunction (ED). The aim of this systematic review and meta-analysis was to evaluate the prevalence of ED and its risk factors in male patients with liver cirrhosis.

methodsA systematic search of PubMed (Medline), EMBASE, OVID Medline, the Cochrane Library, and other databases was performed for this review. Two investigators reviewed the abstracts obtained from the search and selected manuscripts for full-text review. The event rates were calculated with random-effects model and quality effects model.

resultsFourteen studies evaluating ED with the International Index of Erectile Function (IIEF) scores were selected. A total of 770 patients with liver cirrhosis were analyzed. The prevalence of ED in cirrhotic patients was 79% [decompensated: 88.4%, CI 35.95-70.84%, I

conclusionED is relatively common in male patients with cirrhosis, and presence of risk factors increases the prevalence of ED. CLINICAL TRIAL NUMBER: PROSPERO (International Prospective Register of Systematic Reviews), CRD42020220411.

Indexed as

Erectile DysfunctionHumansLiver CirrhosisMalePrevalenceRisk FactorsErectile dysfunctionLiver cirrhosisPrevalenceRisk factorSexual dysfunction

Identifiers

PMID34799837
OpenAlexW3211681802

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.