Evidence map›Paper›PMID 34799624›Full record

ArticleScientific reports2021

In search of different categories of abstract concepts: a fMRI adaptation study.

Francesca Conca, Eleonora Catricalà, Matteo Canini, Alessandro Petrini, Gabriella Vigliocco, Stefano F Cappa, Pasquale Anthony Della Rosa

Registry-linked trialAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07112027 (Exploration of the Neural Correlates of Social Expertise), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07112027 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Exploration of the Neural Correlates of Social Expertise: an Fmri Study Comparing Healthy Individuals With Different Levels and Types of Expertise

TypeinterventionalSponsorUniversità Vita-Salute San RaffaeleRan2025 to 2026Enrolled84ConditionsHealthyArmsBehavioral and MR scanning
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Space and time in words: exploring neural overlap and specificity.Behavioral and brain functions : BBF · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Francesca ConcaICoN Cognitive Neuroscience Center, Institute for Advanced Studies, IUSS Pavia, Palazzo del Broletto, Piazza Vittoria 15, 27100, Pavia, Italy.
Eleonora CatricalàICoN Cognitive Neuroscience Center, Institute for Advanced Studies, IUSS Pavia, Palazzo del Broletto, Piazza Vittoria 15, 27100, Pavia, Italy.
Matteo CaniniUnit of Neuroradiology, IRCCS Ospedale San Raffaele, Milan, Italy.
Alessandro PetriniDepartment of Informatics, Università degli Studi di Milano, Milan, Italy.
Gabriella ViglioccoDepartment of Experimental Psychology, University College London, London, UK.
Stefano F CappaICoN Cognitive Neuroscience Center, Institute for Advanced Studies, IUSS Pavia, Palazzo del Broletto, Piazza Vittoria 15, 27100, Pavia, Italy. stefano.cappa@iusspavia.it.
Pasquale Anthony Della RosaUnit of Neuroradiology, IRCCS Ospedale San Raffaele, Milan, Italy.

Funding

Sixth Framework Programme FP6-2004-NESTPATHSixth Framework Programme grant 028714 to S.F.C. and G.V
6 · The paper itself

Abstract

Concrete conceptual knowledge is supported by a distributed neural network representing different semantic features according to the neuroanatomy of sensory and motor systems. If and how this framework applies to abstract knowledge is currently debated. Here we investigated the specific brain correlates of different abstract categories. After a systematic a priori selection of brain regions involved in semantic cognition, i.e. responsible of, respectively, semantic representations and cognitive control, we used a fMRI-adaptation paradigm with a passive reading task, in order to modulate the neural response to abstract (emotions, cognitions, attitudes, human actions) and concrete (biological entities, artefacts) categories. Different portions of the left anterior temporal lobe responded selectively to abstract and concrete concepts. Emotions and attitudes adapted the left middle temporal gyrus, whereas concrete items adapted the left fusiform gyrus. Our results suggest that, similarly to concrete concepts, some categories of abstract knowledge have specific brain correlates corresponding to the prevalent semantic dimensions involved in their representation.

Indexed as

LanguageAdultBrainBrain MappingCognitionConcept FormationFemaleHumansItalyKnowledgeMagnetic Resonance ImagingMaleReadingReproducibility of ResultsSemanticsTemporal Lobe

Identifiers

PMID34799624
PMCPMC8604982

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.