Evidence map›Paper›PMID 34799600›Full record

ArticleScientific reports2021

Sperm preparedness and adaptation to osmotic and pH stressors relate to functional competence of sperm in Bos taurus.

Maharajan Lavanya, Santhanahalli Siddalingappa Archana, Divakar Swathi, Laxman Ramya, Arunachalam Arangasamy, Balakrishnan Binsila, Arindam Dhali, Narayanan Krishnaswamy, Sanjay Kumar Singh, Harendra Kumar and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Maharajan LavanyaReproductive Physiology Laboratory, Animal Physiology Division, ICAR-National Institute of Animal Nutrition and Physiology, Adugodi, Bengaluru, 560030, India.
Santhanahalli Siddalingappa ArchanaReproductive Physiology Laboratory, Animal Physiology Division, ICAR-National Institute of Animal Nutrition and Physiology, Adugodi, Bengaluru, 560030, India.
Divakar SwathiReproductive Physiology Laboratory, Animal Physiology Division, ICAR-National Institute of Animal Nutrition and Physiology, Adugodi, Bengaluru, 560030, India.
Laxman RamyaReproductive Physiology Laboratory, Animal Physiology Division, ICAR-National Institute of Animal Nutrition and Physiology, Adugodi, Bengaluru, 560030, India.
Arunachalam ArangasamyReproductive Physiology Laboratory, Animal Physiology Division, ICAR-National Institute of Animal Nutrition and Physiology, Adugodi, Bengaluru, 560030, India.
Balakrishnan BinsilaReproductive Physiology Laboratory, Animal Physiology Division, ICAR-National Institute of Animal Nutrition and Physiology, Adugodi, Bengaluru, 560030, India.
Arindam DhaliOmics Laboratory, Bioenergetics and Environmental Sciences Division, ICAR-National Institute of Animal Nutrition and Physiology, Adugodi, Bengaluru, 560030, India.
Narayanan KrishnaswamyIndian Veterinary Research Institute, Bangalore, 560024, India.
Sanjay Kumar SinghDepartment of Animal Reproduction, Indian Veterinary Research Institute, Izatnagar, Bareilly, 243122, India.
Harendra KumarDepartment of Animal Reproduction, Indian Veterinary Research Institute, Izatnagar, Bareilly, 243122, India.
Muniandy SivaramSouthern Regional Station, ICAR-National Dairy Research Institute, Adugodi, Bengaluru, 560030, India.
Sellappan SelvarajuReproductive Physiology Laboratory, Animal Physiology Division, ICAR-National Institute of Animal Nutrition and Physiology, Adugodi, Bengaluru, 560030, India. Selvaraju.S@icar.gov.in.ORCID 0000-0001-5516-238X
National Institute of Animal Nutrition and Physiology · INIndian Veterinary Research Institute · INNational Dairy Research Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The adaptive ability of sperm in the female reproductive tract micromilieu signifies the successful fertilization process. The study aimed to analyze the preparedness of sperm to the prevailing osmotic and pH stressors in the female reproductive tract. Fresh bovine sperm were incubated in 290 (isosmotic-control), 355 (hyperosmotic-uterus and oviduct), and 420 (hyperosmotic-control) mOsm/kg and each with pH of 6.8 (uterus) and 7.4 (oviduct). During incubation, the changes in sperm functional attributes were studied. Sperm kinematics and head area decreased significantly (p < 0.05) immediately upon exposure to hyperosmotic stress at both pH. Proportion of sperm capacitated (%) in 355 mOsm/kg at 1 and 2 h of incubation were significantly (p < 0.05) higher than those in 290 mOsm media. The magnitude and duration of recovery of sperm progressive motility in 355 mOsm with pH 7.4 was correlated with the ejaculate rejection rate (R

Indexed as

OsmoregulationSperm CapacitationSperm MotilityAnimalsBiomechanical PhenomenaCattleCell SurvivalEjaculationFertilinsGlyceraldehyde-3-Phosphate DehydrogenasesHSP90 Heat-Shock ProteinsHydrogen-Ion ConcentrationMaleNFATC Transcription FactorsOsmotic PressureSodium-Hydrogen ExchangersFertilinsGlyceraldehyde-3-Phosphate DehydrogenasesHSP90 Heat-Shock ProteinsNFATC Transcription FactorsSodium-Hydrogen Exchangers

Identifiers

PMID34799600
PMCPMC8604908
OpenAlexW3214135906

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.