Evidence map›Paper›PMID 34799423›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2021

Gα

Claire W Chang, Ni Cheng, Yanyan Bai, Randal A Skidgel, Xiaoping Du

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Monocyte Migration Emerges from a Divergent Chemokine Signaling Network.bioRxiv : the preprint server for biology · 2026
    Article
  3. [Advancement in neutrophil-based drug delivery systems].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2025
    Review
  4. Article
  5. Integrin βNature communications · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Claire W ChangDepartment of Pharmacology, University of Illinois at Chicago, Chicago, IL.ORCID 0000-0002-9258-2540
Ni ChengDepartment of Pharmacology, University of Illinois at Chicago, Chicago, IL.ORCID 0000-0002-9013-690X
Yanyan BaiDepartment of Pharmacology, University of Illinois at Chicago, Chicago, IL.
Randal A SkidgelDupage Medical Technology, Inc., Chicago, IL.
Xiaoping DuDepartment of Pharmacology, University of Illinois at Chicago, Chicago, IL; xdu@uic.edu.
University of Illinois Chicago · USDuPage Medical Group · US

Funding

Mechanisms of integrin signaling and a new anti-platelet/anti-inflammatory approachR35HL150797 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Xiaoping Du · 2020 to 2026
$6.8M
Outside-in signaling mechanisms of platelet integrin alpha-llb-beta3R01HL080264 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DU, XIAOPING · 2007 to 2019
$4.6M
New Strategies for Treating Septic Vasculopathy Inflammation and ThrombosisR01HL125356 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI BONINI, MARCELO G., DU, XIAOPING · 2014 to 2018
$3.4M
Developing a new drug for treating myocardial ischemia/reperfusion injuryR44HL156560 · NHLBI · DUPAGE MEDICAL TECHNOLOGY, INC. · PI SKIDGEL, RANDAL A · 2021 to 2022
$2.0M
Targeting integrin outside-in signaling for treating sepsisR44HL142396 · NHLBI · DUPAGE MEDICAL TECHNOLOGY, INC. · PI SKIDGEL, RANDAL A · 2021 to 2023
$2.0M
Targeting integrin outside-in signaling for treating sepsisR43HL142396 · NHLBI · DUPAGE MEDICAL TECHNOLOGY, INC. · PI DELANEY, MICHAEL KEEGAN, SKIDGEL, RANDAL A · 2018 to 2018
$225k
NHLBI NIH HHS R01 HL080264NHLBI NIH HHS R01 HL125356NHLBI NIH HHS R35 HL150797NHLBI NIH HHS R43 HL142396NHLBI NIH HHS R44 HL142396NHLBI NIH HHS R44 HL156560
6 · The paper itself

Abstract

Neutrophil migration requires β

Indexed as

NeutrophilsTransendothelial and Transepithelial MigrationAnimalsCD18 AntigensCell AdhesionIntegrinsIntercellular Adhesion Molecule-1MiceReceptors, G-Protein-CoupledCD18 AntigensIntegrinsIntercellular Adhesion Molecule-1Receptors, G-Protein-Coupled

Identifiers

PMID34799423
PMCPMC9117564
OpenAlexW3211378427

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.