Evidence map›Paper›PMID 34799252›Full record

ReviewTrends in cognitive sciences2022

Noradrenergic modulation of rhythmic neural activity shapes selective attention.

Martin J Dahl, Mara Mather, Markus Werkle-Bergner

Open access · greenAbstract readReview
In one paragraph

Review in Trends in cognitive sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 160 citations in OpenAlex.

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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Martin J DahlCenter for Lifespan Psychology, Max Planck Institute for Human Development, 14195 Berlin, Germany; Davis School of Gerontology, University of Southern California, 90089 Los Angeles, CA, USA. Electronic address: dahl@mpib-berlin.mpg.de.
Mara MatherDavis School of Gerontology, University of Southern California, 90089 Los Angeles, CA, USA.
Markus Werkle-BergnerCenter for Lifespan Psychology, Max Planck Institute for Human Development, 14195 Berlin, Germany.
Max Planck Institute for Human Development · DEUniversity of Southern California · US

Funding

The Impact of Emotional Regulation on Cognition in AgingR01AG025340 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MATHER, MARA · 2004 to 2021
$7.9M
NIA NIH HHS R01 AG025340
6 · The paper itself

Abstract

During moments involving selective attention, the thalamus orchestrates the preferential processing of prioritized information by coordinating rhythmic neural activity within a distributed frontoparietal network. The timed release of neuromodulators from subcortical structures dynamically sculpts neural synchronization in thalamocortical networks to meet current attentional demands. In particular, noradrenaline modulates the balance of cortical excitation and inhibition, as reflected by thalamocortical alpha synchronization (~8-12 Hz). These neuromodulatory adjustments facilitate the selective processing of prioritized information. Thus, by disrupting effective rhythmic coordination in attention networks, age-related locus coeruleus (LC) degeneration can impair higher levels of neural processing. In sum, findings across different levels of analysis and modalities shed light on how the noradrenergic modulation of neural synchronization helps to shape selective attention.

Indexed as

Locus CoeruleusNorepinephrineHumansNorepinephrinecognitive aginglocus coeruleusnoradrenalinenorepinephrinerhythmic neural activityselective attention

Identifiers

PMID34799252
PMCPMC8678372
OpenAlexW3214337982

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.