Evidence map›Paper›PMID 34798888›Full record

ArticleJournal of nanobiotechnology2021

Atomically precise silver clusterzymes protect mice from radiation damages.

Jiao Guo, Haiyu Yang, Ya Liu, Wei Liu, Ruiying Zhao, He Li, Wei Long, Wenqing Xu, Meili Guo, Xiaodong Zhang

Open access · goldAbstract read
In one paragraph

Article in Journal of nanobiotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Clusterzymes-driven therapy: ultrasmall CuJournal of nanobiotechnology · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jiao Guo *Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300192, China.
Haiyu Yang *Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300192, China.
Ya Liu *Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300192, China.
Wei LiuTianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300192, China.
Ruiying ZhaoDepartment of Physics, School of Science, Tianjin Chengjian University, Tianjin, 300384, China.
He LiTianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300192, China.
Wei LongTianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300192, China. longway@irm-cams.ac.cn.ORCID http://orcid.org/0000-0002-5365-9111
Wenqing XuTianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300192, China. xuwenqing@irm-cams.ac.cn.
Meili GuoDepartment of Physics, School of Science, Tianjin Chengjian University, Tianjin, 300384, China. meiliguo314@163.com.
Xiaodong ZhangDepartment of Physics and Tianjin Key Laboratory of Low Dimensional Materials Physics and Preparing Technology, School of Sciences, Tianjin University, Tianjin, 300350, China. xiaodongzhang@tju.edu.cn.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNTianjin Chengjian University · CNTianjin University of Technology · CN

Funding

national natural science foundation of china 81673106
6 · The paper itself

Abstract

backgroundAs we know, radiotherapy plays an irreplaceable role in the clinical management on solid tumors. However, due to the non-specific killing effects of ionizing radiation, normal tissues damages would be almost simultaneous inevitably. Therefore, ideal radioprotective agents with high efficiency and low toxicity are always desirable. In this work, atomically precise Ag

methodsThe ultra-small glutathione supported Ag

resultsOur studies suggested atomically precise Ag

conclusionIn summary, atomically precise, ultrasmall and water soluble Ag

Indexed as

AntioxidantsGlutathioneRadiation-Protective AgentsSilverAnimalsDNA DamageFemaleMaleMiceMice, Inbred BALB CNanostructuresSuperoxide DismutaseAntioxidantsGlutathioneRadiation-Protective AgentsSilverSuperoxide DismutaseAg14 clusterzymesAtomically preciseRadioprotectionRenal clearance

Identifiers

PMID34798888
PMCPMC8605545
OpenAlexW3211610318

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.