Evidence map›Paper›PMID 34798817›Full record

ArticleBMC geriatrics2021

Impact of the COVID-19 pandemic on symptoms of anxiety and depression and health-related quality of life in older patients with chronic kidney disease.

C G N Voorend, M van Oevelen, M Nieberg, Y Meuleman, C F M Franssen, H Joosten, N C Berkhout-Byrne, A C Abrahams, S P Mooijaart, W J W Bos and 2 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in BMC geriatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

C G N VoorendDepartment of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands. c.g.n.voorend@lumc.nl.
M van OevelenDepartment of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.
M NiebergDepartment of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.
Y MeulemanDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
C F M FranssenDepartment of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
H JoostenDepartment of Internal Medicine, Division of General Internal Medicine, Section Geriatric Medicine, Maastricht University Medical Center+, Maastricht, The Netherlands.
N C Berkhout-ByrneDepartment of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.
A C AbrahamsDepartment of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, The Netherlands.
S P MooijaartDepartment of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.
W J W BosDepartment of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.
M van BurenDepartment of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.
POLDER investigators
Leiden University Medical Center · NLMaastricht University · NLUniversity Medical Center Groningen · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOlder patients with advanced chronic kidney disease are at increased risk for a severe course of the coronavirus disease-2019 (COVID-19) and vulnerable to mental health problems. We aimed to investigate prevalence and associated patient (demographic and clinical) characteristics of mental wellbeing (health-related quality of life [HRQoL] and symptoms of depression and anxiety) before and during the COVID-19 pandemic in older patients with advanced chronic kidney disease.

methodsAn ongoing Dutch multicentre prospective cohort study enrols patients of ≥70 years with an eGFR < 20 mL/min/1.73m

resultsThe 82 included patients had a median age of 77.5 years (interquartile range 73.9-82.1), 77% were male and none had tested positive for COVID-19. Cross-sectionally, 67% of the patients reported to be more anxious about COVID-19 because of their kidney disease, and 43% of the patients stated that their quality of life was reduced due to the COVID-19 pandemic. Compared to pre-COVID-19, the presence of depressive symptoms had increased (11 to 22%; p = .022) and physical HRQoL declined (M = 40.4, SD = 10.1 to M = 36.1, SD = 10.4; p < .001), particularly in males. Mental HRQoL (M = 50.3, SD = 9.6 to M = 50.4, SD = 9.9; p = .913) and emotional symptoms remained similar.

conclusionsOlder patients with advanced chronic kidney disease suffered from disease-related anxiety about COVID-19, increased depressive symptoms and reduced physical HRQoL during the COVID-19 pandemic. The impact of the pandemic on this vulnerable patient group extends beyond increased mortality risk, and awareness of mental wellbeing is important.

trial registrationThe study is registered at the Netherlands Trial Register (NTR), trial number NL7104. Date of registration: 06-06-2018.

Indexed as

COVID-19Renal Insufficiency, ChronicAgedAnxietyDepressionHumansMalePandemicsProspective StudiesQuality of LifeSARS-CoV-2AgedChronic kidney diseasesCoronavirus disease-2019 (COVID-19) pandemicMental healthQuality of life

Identifiers

PMID34798817
PMCPMC8602979
OpenAlexW3213629734

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.