Evidence map›Paper›PMID 34798545›Full record

ArticleEpidemics2021

Assessing the efficacy of interventions to control indoor SARS-Cov-2 transmission: An agent-based modeling approach.

Trevor S Farthing, Cristina Lanzas

Abstract read
In one paragraph

Article in Epidemics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
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  6. Review
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  11. Article
  12. A Vaccination Simulator for COVID-19: Effective and Sterilizing Immunization Cases.IEEE journal of biomedical and health informatics · 2021
    Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Trevor S FarthingNorth Carolina State University, Raleigh, NC, USA.
Cristina LanzasNorth Carolina State University, Raleigh, NC, USA. Electronic address: clanzas@ncsu.edu.

Funding

Analytical pipelines for data and model integration: finding informed pathways for antimicrobial resistance controlR35GM134934 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI LANZAS, CRISTINA · 2020 to 2024
$2.1M
ACL HHS U01CK000587NCEZID CDC HHS U01 CK000587NIGMS NIH HHS R35 GM134934
6 · The paper itself

Abstract

Nonpharmaceutical interventions for minimizing indoor SARS-CoV-2 transmission continue to be critical tools for protecting susceptible individuals from infection, even as effective vaccines are produced and distributed globally. We developed a spatially-explicit agent-based model for simulating indoor respiratory pathogen transmission during discrete events taking place in a single room within a sub-day time frame, and used it to compare effects of four interventions on reducing secondary SARS-CoV-2 attack rates during a superspreading event by simulating a well-known case study. We found that preventing people from moving within the simulated room and efficacious mask usage appear to have the greatest effects on reducing infection risk, but multiple concurrent interventions are required to minimize the proportion of susceptible individuals infected. Social distancing had little effect on reducing transmission if individuals were randomly relocated within the room to simulate activity-related movements during the gathering. Furthermore, our results suggest that there is potential for ventilation airflow to expose susceptible people to aerosolized pathogens even if they are relatively far from infectious individuals. Maximizing the vertical aerosol removal rate is paramount to successful transmission-risk reduction when using ventilation systems as intervention tools.

Indexed as

COVID-19SARS-CoV-2HumansSystems AnalysisAerosolAgent-based modelCOVID-19DropletIndoor transmissionSARS-CoV-2

Identifiers

PMID34798545
PMCPMC8588587

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.