Evidence map›Paper›PMID 34797840›Full record

ArticlePloS one2021

Relationship between out-of-hospital cardiac arrests and COVID-19 during the first and second pandemic wave. The importance of monitoring COVID-19 incidence.

Enrico Baldi, Roberto Primi, Sara Bendotti, Alessia Currao, Sara Compagnoni, Francesca Romana Gentile, Giuseppe Maria Sechi, Claudio Mare, Alessandra Palo, Enrico Contri and 14 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
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  3. Article
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  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 4 institutions in 1 country.

Enrico BaldiDepartment of Molecular Medicine, Section of Cardiology, University of Pavia, Pavia, Italy.
Roberto PrimiDivision of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.ORCID 0000-0002-4271-6248
Sara BendottiDivision of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Alessia CurraoDivision of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Sara CompagnoniDepartment of Molecular Medicine, Section of Cardiology, University of Pavia, Pavia, Italy.
Francesca Romana GentileDepartment of Molecular Medicine, Section of Cardiology, University of Pavia, Pavia, Italy.
Giuseppe Maria SechiAgenzia Regionale Emergenza Urgenza, Milan, Italy.
Claudio MareAgenzia Regionale Emergenza Urgenza, Milan, Italy.
Alessandra PaloAAT Pavia - Agenzia Regionale Emergenza Urgenza (AREU) c/o Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Enrico ContriAAT Pavia - Agenzia Regionale Emergenza Urgenza (AREU) c/o Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Vincenza RonchiAAT Pavia - Agenzia Regionale Emergenza Urgenza (AREU) c/o Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Giuseppe BergaminiAAT Lodi - Agenzia Regionale Emergenza Urgenza (AREU) c/o ASST di Lodi, Lodi, Italy.
Francesca RealiAAT Lodi - Agenzia Regionale Emergenza Urgenza (AREU) c/o ASST di Lodi, Lodi, Italy.
Pierpaolo ParogniAAT Mantova - Agenzia Regionale Emergenza Urgenza (AREU) c/o ASST di Mantua, Mantua, Italy.
Fabio FacchinAAT Mantova - Agenzia Regionale Emergenza Urgenza (AREU) c/o ASST di Mantua, Mantua, Italy.ORCID 0000-0002-1189-0323
Ugo RizziAAT Cremona - Agenzia Regionale Emergenza Urgenza (AREU) c/o ASST di Cremona, Cremona, Italy.
Daniele BussiAAT Cremona - Agenzia Regionale Emergenza Urgenza (AREU) c/o ASST di Cremona, Cremona, Italy.
Simone RuggeriAAT Cremona - Agenzia Regionale Emergenza Urgenza (AREU) c/o ASST di Cremona, Cremona, Italy.
Sabina CampiAAT Varese - Agenzia Regionale Emergenza Urgenza (AREU) c/o ASST dei Sette Laghi, Varese, Italy.
Paola CentineoAAT Varese - Agenzia Regionale Emergenza Urgenza (AREU) c/o ASST dei Sette Laghi, Varese, Italy.
Roberto De PontiASST-Settelaghi, Ospedale di Circolo - Università dell'Insubria, Varese, Italy.
Luigi Oltrona ViscontiDivision of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Simone SavastanoDivision of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.ORCID 0000-0002-9789-6661
all the Lombardia CARe researchers
Agenzia Regionale Emergenza Urgenza · ITPoliclinico San Matteo Fondazione · ITUniversity of Pavia · ITUniversity of Insubria · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe relationship between COVID-19 and out-of-hospital cardiac arrests (OHCAs) has been shown during different phases of the first pandemic wave, but little is known about how to predict where cardiac arrests will increase in case of a third peak.

aimTo seek for a correlation between the OHCAs and COVID-19 daily incidence both during the two pandemic waves at a provincial level.

methodsWe considered all the OHCAs occurred in the provinces of Pavia, Lodi, Cremona, Mantua and Varese, in Lombardy Region (Italy), from 21/02/2020 to 31/12/2020. We divided the study period into period 1, the first 157 days after the outbreak and including the first pandemic wave and period 2, the second 158 days including the second pandemic wave. We calculated the cumulative and daily incidence of OHCA and COVID-19 for the whole territory and for each province for both periods.

resultsA significant correlation between the daily incidence of COVID-19 and the daily incidence of OHCAs was observed both during the first and the second pandemic period in the whole territory (R = 0.4, p<0.001 for period 1 and 2) and only in those provinces with higher COVID-19 cumulative incidence (period 1: Cremona R = 0.3, p = 0.001; Lodi R = 0.4, p<0.001; Pavia R = 0.3; p = 0.01; period 2: Varese R = 0.4, p<0.001).

conclusionsOur results suggest that strictly monitoring the pandemic trend may help in predict which territories will be more likely to experience an OHCAs' increase. That may also serve as a guide to re-allocate properly health resources in case of further pandemic waves.

Indexed as

AgedAged, 80 and overCOVID-19Epidemiological MonitoringFemaleHumansIncidenceItalyMaleMiddle AgedOut-of-Hospital Cardiac Arrest

Identifiers

PMID34797840
PMCPMC8604324
OpenAlexW3212423742

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.