Evidence map›Paper›PMID 34797697›Full record

Trial reportJCO global oncology2021

Oncologic Home-Hospitalization Delivers a High-Quality and Patient-Centered Alternative to Standard Ambulatory Care: Results of a Randomized-Controlled Equivalence Trial.

Lieselot Cool, Jana Missiaen, Philip Debruyne, Hans Pottel, Veerle Foulon, Tessa Lefebvre, Laura Tack, Petra Archie, Dominique Vandijck, Koen Van Eygen

Abstract readRandomized Controlled TrialEquivalence Trial
In one paragraph

Trial report in JCO global oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Acute oncology hospital care at home for post-chemotherapy monitoring.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  3. Article
  4. Home-Based Daratumumab in Patients With Multiple Myeloma.European journal of haematology · 2025
    Observational
  5. Onco@home: comparing the costs and reimbursement of cancer treatment at home with the standard of care.Archives of public health = Archives belges de sante publique · 2024
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lieselot CoolCancer Centre, General Hospital Groeninge, Kortrijk, Belgium.
Jana MissiaenCancer Centre, General Hospital Groeninge, Kortrijk, Belgium.
Philip DebruyneCancer Centre, General Hospital Groeninge, Kortrijk, Belgium.ORCID 0000-0001-5438-9697
Hans PottelDepartment of Public Health and Primary Care @ Kulak, Catholic University Leuven Kulak Etienne Sabbelaan, Kortrijk, Belgium.ORCID 0000-0003-0074-8919
Veerle FoulonDepartment of Pharmaceutical and Pharmacological Sciences, Catholic University Leuven, Leuven, Belgium.
Tessa LefebvreCancer Centre, General Hospital Groeninge, Kortrijk, Belgium.
Laura TackCancer Centre, General Hospital Groeninge, Kortrijk, Belgium.
Petra ArchieCancer Centre, General Hospital Groeninge, Kortrijk, Belgium.
Dominique VandijckFaculty of Medicine and Health Sciences, Ghent University, Gent, Belgium.
Koen Van EygenCancer Centre, General Hospital Groeninge, Kortrijk, Belgium.ORCID 0000-0001-8285-906X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeGiven the increasing burden of cancer on patients, health care providers, and payers, the shift of certain outpatient procedures to the patients' homes (further indicated as oncologic home-hospitalization [OHH]) might be a high-quality, patient-centered, and cost-effective alternative to standard ambulatory cancer care (SOC).

methodsA randomized-controlled trial was conducted to evaluate the quality of a locally implemented model for OHH (n = 74) compared with SOC (n = 74). The model for OHH consisted of home administration of certain subcutaneous cancer drugs (full OHH) and home nursing assessments before ambulatory systemic cancer therapy (partial OHH). Quality was evaluated based on patient-reported quality of life (QoL) and related end points; service use and cost data; safety data; patient-reported satisfaction and preferences; and model efficiency. An equivalence design was used for primary end point analysis. Participants were followed during 12 weeks of systemic cancer treatment.

resultsThis trial demonstrated equivalence of both models (OHH

conclusionThe shift of particular procedures from the outpatient clinic to the patients' homes offers a high-quality and patient-centered alternative for a large proportion of patients with cancer. Further research is needed to evaluate potential cost-efficiency.

Indexed as

NeoplasmsQuality of LifeAmbulatory CareHospitalizationHumansMedical OncologyPatient-Centered Care

Identifiers

PMID34797697
PMCPMC8613347

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.