ArticlePaediatric and perinatal epidemiology2022
The association between wildfire exposure in pregnancy and foetal gastroschisis: A population-based cohort study.
Article in Paediatric and perinatal epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 39 citations in OpenAlex.
- Wildland fire smoke and birth defects in California.Journal of exposure science & environmental epidemiology · 2026Article
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- Climate Change and Reproductive Health.Endocrine reviews · 2025Review
- Co-occurring climate events and environmental justice in California, 2018-2019.Environmental research, health : ERH · 2025Article
- The Camp fire and perinatal health: an example of the generalized synthetic control method to identify susceptible windows of exposure.American journal of epidemiology · 2025Article
- Living Near Wildfires and the Risk of Fetal Congenital Heart Defects: Evaluating Critical Windows of Vulnerability.AJP reports · 2025Article
- Physicochemical Characterization of the Particulate Matter in New Jersey/New York City Area, Resulting from the Canadian Quebec Wildfires in June 2023.Environmental science & technology · 2024Article
- Earth at risk: An urgent call to end the age of destruction and forge a just and sustainable future.PNAS nexus · 2024Review
- Obstetric care for environmental migrants.Irish journal of medical science · 2024Review
- Article
- "Air That Once Was Breath" Part 2: Wildfire Smoke and Airway Disease - "Climate Change, Allergy and Immunology" Special IAAI Article Collection: Collegium Internationale Allergologicum Update 2023.International archives of allergy and immunology · 2024Review
- [The climate crisis as an ethical challenge].Wiener medizinische Wochenschrift (1946) · 2023Article
- The Alberta Congenital Anomalies Surveillance System: a 40-year review with prevalence and trends for selected congenital anomalies, 1997-2019.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2023Article
- Birth Outcomes, Health, and Health Care Needs of Childbearing Women following Wildfire Disasters: An Integrative, State-of-the-Science Review.Environmental health perspectives · 2022Review
- Wildfires in Pregnancy: Potential Threats to the Newborn.Paediatric and perinatal epidemiology · 2022Article
- Impact of climate change on surgery: A scoping review to define existing knowledge and identify gaps.The journal of climate change and healthArticle
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGlobal climate change has led to an increase in the prevalence and severity of wildfires. Pollutants released into air, soil and groundwater from wildfires may impact embryo development leading to gastroschisis.
objectiveThe objective of this study was to determine the association between wildfire exposure before and during pregnancy and the risk of foetal gastroschisis development.
methodsThis was a retrospective cohort study using The California Office of Statewide Health Planning and Development Linked Birth File linked to The California Department of Forestry and Fire Protection data between 2007 and 2010. Pregnancies complicated by foetal gastroschisis were identified by neonatal hospital discharge ICD-9 code. Pregnancies were considered exposed to wildfire if the mother's primary residence zip code was within 15 miles to the closest edge of a wildfire. The exposure was further stratified by trimester or if exposed within 30 days prior to pregnancy. Multivariable log-binomial regression analyses were performed to estimate the association between wildfire exposure in each pregnancy epoch and foetal gastroschisis.
resultsBetween 2007 and 2010, 844,348 (40%) births were exposed to wildfire in California. Compared with births without wildfire exposure, those with first-trimester exposure were associated with higher rates of gastroschisis, 7.8 vs. 5.7 per 10,000 births (adjusted relative risk [aRR] 1.28, 95% confidence interval [CI] 1.07, 1.54). Furthermore, those with prepregnancy wildfire exposure were also found to have higher rates of gastroschisis, 12.5 vs. 5.7 per 10,000 births, (aRR 2.17, 95% CI 1.42, 3.52). In contrast, second- and third-trimester wildfire exposures were not associated with foetal gastroschisis.
conclusionsWildfire exposure within 30 days before pregnancy was associated with more than two times higher risk of foetal gastroschisis, whereas a 28% higher risk was demonstrated if exposure was in the first trimester.
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