Evidence map›Paper›PMID 34797488›Full record

ArticleClinical journal of gastroenterology2022

Intra-abdominal bleeding caused by amyloid transthyretin amyloidosis in the gastrointestinal tract: a case report.

Shinsei Yumoto, Koichi Doi, Takaaki Higashi, Yoshiya Shimao, Mitsuharu Ueda, Akira Ishihara, Yuki Adachi, Hiroyuki Ishiodori, Shinobu Honda, Hideo Baba

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Clinical journal of gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Shinsei YumotoDepartment of Surgery, Miyazaki Prefectural Nobeoka Hospital, Miyazaki, Japan.
Koichi DoiDepartment of Surgery, Miyazaki Prefectural Nobeoka Hospital, Miyazaki, Japan.
Takaaki HigashiDepartment of Surgery, Miyazaki Prefectural Nobeoka Hospital, Miyazaki, Japan.
Yoshiya ShimaoDepartment of Pathology, Miyazaki Prefectural Nobeoka Hospital, 2-1-10 Shinkouji, Nobeoka, Miyazaki, 882-0835, Japan.
Mitsuharu UedaDepartment of Neurology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Akira IshiharaDepartment of Pathology, Junwakai Memorial Hospital, Miyazaki, Japan.
Yuki AdachiDepartment of Surgery, Miyazaki Prefectural Nobeoka Hospital, Miyazaki, Japan.
Hiroyuki IshiodoriDepartment of Surgery, Miyazaki Prefectural Nobeoka Hospital, Miyazaki, Japan.
Shinobu HondaDepartment of Surgery, Miyazaki Prefectural Nobeoka Hospital, Miyazaki, Japan.
Hideo BabaDepartment of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan. hdobaba@kumamoto-u.ac.jp.ORCID http://orcid.org/0000-0002-2129-9086
Miyazaki Prefectural Hospital · JPKumamoto University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diagnosis of gastrointestinal (GI) amyloidosis is often very difficult because of its nonspecific symptoms. However, a few reports have indicated that serious symptoms such as fatal GI bleeding and obstruction or perforation sometimes lead to a diagnosis of GI amyloidosis. A 79-year-old man was transported to our emergency department with a 1-week history of worsening abdominal pain. Abdominal contrast-enhanced computed tomography showed extravasation from part of the transverse colon wall and moderate ascites. Because intra-abdominal bleeding was suspected, the patient urgently underwent partial resection of the transverse colon, which was the source of the bleeding. Postoperative pathological examination of the tissue specimens led to a diagnosis of amyloid transthyretin amyloidosis. This is the first reported case in which intra-abdominal bleeding led to a diagnosis of GI amyloidosis. We should consider the possibility of GI amyloidosis when intraperitoneal bleeding is observed in elderly patients.

Indexed as

Amyloid Neuropathies, FamilialGastrointestinal DiseasesAgedGastrointestinal HemorrhageHumansMaleAmyloid transthyretin amyloidosisGastrointestinal amyloidosisIntra-abdominal bleeding

Identifiers

PMID34797488
OpenAlexW3212047491

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.