SynthesisNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2022
The effect of obstructive sleep apnea on the increased risk of cardiovascular disease: a systematic review and meta-analysis.
Synthesis in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07364318 (Cognitive Function and Pathophysiological Mechanisms in Adults With Obstructive Sleep Apnea), which is not on this map. Cited by 63 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cognitive Function and Pathophysiological Mechanisms in Adults With Obstructive Sleep Apnea: Long-term Impact of Positive Airway Pressure Therapy
Who cites it
63 citing papers in PubMed, 3 syntheses or guidelines pooled it, 98 citations in OpenAlex.
- Pooled it
- Sleep Problems Associate With Multimorbidity: A Systematic Review and Meta-analysis.Public health reviews · 2023Pooled it
- The impact of continuous positive airway pressure on cardiac mechanics: Findings from a meta-analysis of echocardiographic studies.Journal of clinical hypertension (Greenwich, Conn.) · 2022Pooled it
- Effects of acute exercise performed at different times of day on respiratory, blood pressure, and cardiac autonomic modulation outcomes in patients with obstructive sleep apnea: a randomized crossover trial.Journal of human hypertension · 2025Trial
- Association between early body weight reduction and treatment outcomes in participants with obstructive sleep apnoea and obesity: a post hoc analysis of SURMOUNT-OSA trials.EClinicalMedicine · 2026Article
- Sex Differences in Sleep Duration and Quality: Implications for Hypertension Risk.Current hypertension reports · 2026Review
- Article
- Impact of Sleep Health Domains on Chronic Conditions: Findings from a Cross-Sectional Analysis Using Data from the NHANES 2017-2020.Sleep science (Sao Paulo, Brazil) · 2026Article
- Effects of Positive Airway Pressure Therapy on Cognitive Function in Patients with Obstructive Sleep Apnea: A Prospective Observational Study Protocol.Life (Basel, Switzerland) · 2026Article
- Assessing ChatGPT Responses to Commonly Asked Questions About Hypoglossal Nerve Stimulation.World journal of otorhinolaryngology - head and neck surgery · 2026Article
- Effectiveness of transoral robotic surgery of the base of the tongue vs. conservative treatment for obstructive sleep apnea, a RCT, the RAPID study protocol.Contemporary clinical trials communications · 2026Article
- Impact of obstructive lung disease and sleep apnea symptoms on cardiovascular risk and all-cause mortality: insights from a community-dwelling cohort.Sleep & breathing = Schlaf & Atmung · 2026Article
- Patient Perspectives of a Sleep Apnea Treatment Adherence Intervention Adapted for Persons with Traumatic Brain Injury.Brain injury · 2025Article
- Cross-Sectional Analysis of Sleep Quality and Vascular Health in Shift- and Day-Working Nurses.Clocks & sleep · 2025Article
- Relationship of Circadian Blood Pressure Dysregulation With Left Ventricular Structure and Function in Children With Obstructive Sleep Apnea.Journal of sleep research · 2025Observational
- Sex Differences in Predictors of Obstructive Sleep Apnea Risk Among Young Adults: A Cross-Sectional Study in Colombian University Students.Journal of clinical medicine · 2025Article
- Relationship between sleep apnea and dizziness: a scoping review.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Article
- Sleep apnea increases odds of 90-day postoperative complications and healthcare utilization following lumbar discectomy.North American Spine Society journal · 2025Article
- Patients' experiences of barriers and facilitators with continuous positive airway pressure therapy in obstructive sleep apnoea - a qualitative interview study.Archives of public health = Archives belges de sante publique · 2025Article
- CA125 as a Biomarker for Identifying Disease Severity and Right Ventricular Dysfunction in Obstructive Sleep Apnea.Anatolian journal of cardiology · 2025Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundObstructive sleep apnea (OSA) is a disorder characterized by intermittent airway obstruction during sleep. The association between OSA and the incidence of cardiovascular disease (CVD) has been investigated in many studies; however, the results are not entirely consistent between studies. The aim of this study was to investigate the relationship between OSA and the risk of CVD through a meta-analysis of cohort studies.
methodsA systematic review and meta-analysis of literature was conducted using the PubMed, WoS, Embase, ScienceDirect, Scopus, and Web of Science databases up to the year 2020. In order to analyze the eligible studies, the stochastic effects model was used and the heterogeneity of the studies with the I
resultsA total of 24 studies were included in the meta-analysis according to the inclusion criteria. Twelve studies reported CVD results, 11 studies reported stroke results, 9 studies reported mortality results, and 8 studies reported CVD results. The odds ratio of CVD in patients with OSA 1.71 (1.17-2.27: 95% confidence interval) stroke in patients with OSA, 1.86 (1.28-2.69: 95% confidence interval), mortality in patients with OSA, 1.77 (1.37-2.29: 95% confidence interval) and CHD in patients with OSA, and 1.48 (1.06-2.28: 95% confidence interval) was obtained.
conclusionOSA is considered a cardiovascular risk factor. There is a relationship between the severity of OSA and the risk of cardiovascular disease. OSA increases the risk of heart attack, CHD, and death from cardiovascular disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.