Evidence map›Paper›PMID 34797348›Full record

ArticleMedicine2021

Synergistic effects of herbal medicines and anticancer drugs: A protocol for systematic review and meta-analysis.

Chunhoo Cheon

Open access · goldAbstract read
In one paragraph

Article in Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Cancer management and research · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Chunhoo CheonDepartment of Preventive Medicine, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.ORCID 0000-0002-7078-0079
Kyung Hee University · KR

Funding

Korea Health Industry Development Institute HI18C2382National Research Foundation of Korea 2020R1A5A2019413
6 · The paper itself

Abstract

backgroundAn increasing number of studies have been reporting combination therapy using herbal medicines and anticancer drugs, and the synergistic effects of this combination have gained much attention across the medical community. In this study, we will review and summarize all published studies that have investigated the synergistic interaction between herbal medicines and anticancer drugs.

methodsWe will search the PubMed, Embase, and Cochrane Library databases. Studies investigated the synergistic interaction between herbal medicines and anticancer drugs will be included. The selection and extraction process will be performed by 2 independent reviewers, and we will perform qualitative synthesis. DISCUSSION: The present study is being performed to investigate the herbal medicines and anticancer drugs that are used concomitantly, and to determine the combinations that are expected to show a synergistic effect. This knowledge will provide new insights into the possible role of herbal medicines in anticancer treatment. REVIEW REGISTRATION: Trial registration: OSF Registration number: DOI 10.17605/OSF.IO/H5QS9.

Indexed as

Drug SynergismPlants, MedicinalAntineoplastic AgentsComplementary TherapiesDrugs, Chinese HerbalHumansMeta-Analysis as TopicNeoplasmsSystematic Reviews as TopicAntineoplastic AgentsDrugs, Chinese Herbal

Identifiers

PMID34797348
PMCPMC8601363
OpenAlexW3213695135

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.