Evidence map›Paper›PMID 34796878›Full record

ArticleEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2021

Transcatheter treatment for tricuspid valve disease.

Fabien Praz, Denisa Muraru, Felix Kreidel, Philipp Lurz, Rebecca T Hahn, Victoria Delgado, Michele Senni, Ralph Stephan von Bardeleben, Georg Nickenig, Jörg Hausleiter and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 141 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
141citing papers in PubMed, 4 pooled it
32.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

141 citing papers in PubMed, 4 syntheses or guidelines pooled it, 291 citations in OpenAlex.

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  20. 2025 ESC/EACTS valvular heart disease guidelines: practical updates on mitral and tricuspid regurgitation.European heart journal supplements : journal of the European Society of Cardiology · 2026
    Article

81 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 12 institutions in 8 countries.

Fabien PrazBern University Hospital, University of Bern, Bern, Switzerland.
Denisa Muraru
Felix Kreidel
Philipp Lurz
Rebecca T Hahn
Victoria Delgado
Michele Senni
Ralph Stephan von Bardeleben
Georg Nickenig
Jörg Hausleiter
Antonio Mangieri
Jose L Zamorano
Bernard D Prendergast
Francesco Maisano
Johannes Gutenberg University Mainz · DEColumbia University Irving Medical Center · USInstituto Cajal · ESIRCCS Ospedale San Raffaele · ITLeiden University Medical Center · NLLeipzig Heart Institute · DELudwig-Maximilians-Universität München · DEMaria Cecilia Hospital · ITOspedale Papa Giovanni XXIII · ITSt Thomas' Hospital · GBUniversity Hospital Bonn · DEUniversity of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Approximately 4% of subjects aged 75 years or more have clinically relevant tricuspid regurgitation (TR). Primary TR results from anatomical abnormality of the tricuspid valve apparatus and is observed in only 8-10% of the patients with tricuspid valve disease. Secondary TR is more common and arises as a result of annular dilation caused by right ventricular enlargement and dysfunction as a consequence of pulmonary hypertension, often caused by left-sided heart disease or atrial fibrillation. Irrespective of its aetiology, TR leads to volume overload and increased wall stress, both of which negatively contribute to detrimental remodelling and worsening TR. This vicious circle translates into impaired survival and increased heart failure symptoms in patients with and without reduced left ventricular ejection fraction. Interventions to correct TR are underutilised in daily clinical practice owing to increased surgical risk and late patient presentation. The recently introduced transcatheter tricuspid valve interventions aim to address this unmet need. Dedicated expertise and an interdisciplinary Heart Team evaluation are essential to integrate these new techniques successfully and select patients. The present article proposes a standardised approach to evaluate patients with TR who may be candidates for transcatheter interventions. In addition, a state-of-the-art review of the available transcatheter therapies, the main criteria for patient and device selection, and information concerning the remaining uncertainties are provided.

Indexed as

Heart Valve DiseasesHeart Valve Prosthesis ImplantationTricuspid Valve InsufficiencyHumansStroke VolumeTreatment OutcomeTricuspid ValveVentricular Function, Left

Identifiers

PMID34796878
PMCPMC9724890
OpenAlexW3212684942

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.