Evidence map›Paper›PMID 34796680›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2022

Mesoporous Bioactive Glasses in Cancer Diagnosis and Therapy: Stimuli-Responsive, Toxicity, Immunogenicity, and Clinical Translation.

Esmaeel Sharifi, Ashkan Bigham, Satar Yousefiasl, Maria Trovato, Matineh Ghomi, Yasaman Esmaeili, Pouria Samadi, Ali Zarrabi, Milad Ashrafizadeh, Shokrollah Sharifi and 14 more

Open access · goldAbstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 1 pooled it
8.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 1 synthesis or guideline pooled it, 133 citations in OpenAlex.

  1. Pooled it
  2. Tumor Exposomics: A New Paradigm for Individualized Continuous Exposure Monitoring.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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  17. Life (Basel, Switzerland) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 14 institutions in 6 countries.

Esmaeel SharifiDepartment of Tissue Engineering and Biomaterials, School of Advanced Medical Sciences and Technologies, Hamadan University of Medical Sciences, Hamadan, 6517838736, Iran.ORCID 0000-0003-3400-3106
Ashkan BighamInstitute of Polymers, Composites and Biomaterials, National Research Council (IPCB-CNR), Naples, 80125, Italy.
Satar YousefiaslSchool of Dentistry, Hamadan University of Medical Sciences, Hamadan, 6517838736, Iran.
Maria TrovatoInstitute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), Naples, 80131, Italy.
Matineh GhomiChemistry Department, Faculty of Science, Shahid Chamran University of Ahvaz, Ahvaz, 61537-53843, Iran.
Yasaman EsmaeiliBiosensor Research Center, School of Advanced Technologies in Medicine, Isfahan University of Medical Sciences, Isfahan, 8174673461, Iran.
Pouria SamadiResearch Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, 6517838736, Iran.
Ali ZarrabiSabanci University Nanotechnology Research and Application Center (SUNUM), Tuzla, Istanbul, 34956, Turkey.
Milad AshrafizadehFaculty of Engineering and Natural Sciences, Sabanci University, Orta Mahalle, Üniversite Caddesi No. 27, Orhanlı, Tuzla, Istanbul, 34956, Turkey.
Shokrollah SharifiDepartment of Mechanical Engineering, University of Melbourne, Melbourne, 3010, Australia.
Rossella SartoriusInstitute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), Naples, 80131, Italy.
Farnaz Dabbagh MoghaddamDepartment of Biology, Science and Research Branch, Islamic Azad University, Tehran, 1477893855, Iran.
Aziz MalekiDepartment of Pharmaceutical Nanotechnology, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, 45139-56184, Iran.
Hao SongAustralian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, 4072, Australia.
Tarun AgarwalDepartment of Biotechnology, Indian Institute of Technology, Kharagpur, 721302, India.
Tapas Kumar MaitiDepartment of Biotechnology, Indian Institute of Technology, Kharagpur, 721302, India.
Nasser NikfarjamDepartment of Chemistry, Institute for Advanced Studies in Basic Sciences (IASBS), Zanjan, 45137-66731, Iran.
Colin BurvillDepartment of Mechanical Engineering, University of Melbourne, Melbourne, 3010, Australia.
Virgilio MattoliIstituto Italiano di Tecnologia, Centre for Materials Interface, Pontedera, Pisa, 56025, Italy.
Maria Grazia RaucciInstitute of Polymers, Composites and Biomaterials, National Research Council (IPCB-CNR), Naples, 80125, Italy.
Kai ZhengIstituto Italiano di Tecnologia, Centre for Materials Interface, Pontedera, Pisa, 56025, Italy.
Aldo R BoccacciniInstitute of Biomaterials, University of Erlangen-Nuremberg, Erlangen, 91058, Germany.
Luigi AmbrosioInstitute of Polymers, Composites and Biomaterials, National Research Council (IPCB-CNR), Naples, 80125, Italy.
Pooyan MakvandiChemistry Department, Faculty of Science, Shahid Chamran University of Ahvaz, Ahvaz, 6153753843, Iran.ORCID 0000-0003-2456-0961
National Research Council · ITHamedan University of Medical Sciences · IRIndian Institute of Technology Kharagpur · INPiaggio (Italy) · ITSabancı Üniversitesi · TRThe University of Melbourne · AUDamghan University · IRFriedrich-Alexander-Universität Erlangen-Nürnberg · DEInstitute for Advanced Studies in Basic Sciences · IRIsfahan University of Medical Sciences · IRIslamic Azad University, Science and Research Branch · IRShahid Chamran University of Ahvaz · IRThe University of Queensland · AUZanjan University of Medical Sciences · IR

Funding

German Research Foundation BO 1191/23-1National Institutes for Medical Research Development 943258Progetto MIUR PRIN2017-ACTION 2017SZ5WZB
6 · The paper itself

Abstract

Cancer is one of the top life-threatening dangers to the human survival, accounting for over 10 million deaths per year. Bioactive glasses have developed dramatically since their discovery 50 years ago, with applications that include therapeutics as well as diagnostics. A new system within the bioactive glass family, mesoporous bioactive glasses (MBGs), has evolved into a multifunctional platform, thanks to MBGs easy-to-functionalize nature and tailorable textural properties-surface area, pore size, and pore volume. Although MBGs have yet to meet their potential in tumor treatment and imaging in practice, recently research has shed light on the distinguished MBGs capabilities as promising theranostic systems for cancer imaging and therapy. This review presents research progress in the field of MBG applications in cancer diagnosis and therapy, including synthesis of MBGs, mechanistic overview of MBGs application in tumor diagnosis and drug monitoring, applications of MBGs in cancer therapy ( particularly, targeted delivery and stimuli-responsive nanoplatforms), and immunological profile of MBG-based nanodevices in reference to the development of novel cancer therapeutics.

Indexed as

AnimalsDisease Models, AnimalGlassHyperthermia, InducedMiceNanomedicineNeoplasmsPhotochemotherapyPhotothermal TherapyPorositycancer therapydiagnosisgene and drug deliveryimmunotherapymesoporous bioactive glassestoxicological profile

Identifiers

PMID34796680
PMCPMC8805580
OpenAlexW3211670717

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.