Evidence map›Paper›PMID 34796486›Full record

ArticleJournal of child psychology and psychiatry, and allied disciplines2022

Parenting moderates the etiology of callous-unemotional traits in middle childhood.

Rachel C Tomlinson, Luke W Hyde, Hailey L Dotterer, Kelly L Klump, S Alexandra Burt

Abstract read
In one paragraph

Article in Journal of child psychology and psychiatry, and allied disciplines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Annual Research Review: Early conduct problems - precursors, outcomes, and etiology.Journal of child psychology and psychiatry, and allied disciplines · 2026
    Review
  5. Article
  6. The Evolving ADHD Phenotype in the Externalizing Context.The American journal of psychiatry · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Novel measures of family orientation and childhood self-regulation: A genetically informed twin study.Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43) · 2023
    Observational
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rachel C TomlinsonDepartment of Psychology, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0003-4349-0081
Luke W HydeDepartment of Psychology, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-5947-7896
Hailey L DottererDepartment of Psychology, University of Michigan, Ann Arbor, MI, USA.
Kelly L KlumpDepartment of Psychology, Michigan State University, East Lansing, MI, USA.
S Alexandra BurtDepartment of Psychology, Michigan State University, East Lansing, MI, USA.

Funding

Integrating contextual, proximal, and individual risks for child conduct problemsR01HD066040 · NICHD · MICHIGAN STATE UNIVERSITY · PI BURT, S. ALEXANDRA · 2010 to 2014
$2.9M
Gene-environment Interactions in Childhood Conduct ProblemsR01MH081813 · NIMH · MICHIGAN STATE UNIVERSITY · PI BURT, S. ALEXANDRA · 2008 to 2013
$1.6M
Division of Graduate Education DGE 1256260Division of Graduate Education DGE 1650114NICHD NIH HHS R01 HD066040NIMH NIH HHS R01 MH081813
6 · The paper itself

Abstract

backgroundCallous-unemotional (CU) traits are associated with chronic and escalating trajectories of antisocial behavior. Extant etiologic studies suggest that heritability estimates for CU traits vary substantially, while also pointing to an environmental association between parenting and CU traits.

methodsWe used twin modeling to estimate additive genetic (A), shared environmental (C), and nonshared environmental (E) influences on CU traits, measured with the Inventory of Callous-Unemotional Traits (ICU) and its subscales. Our sample included 600 twin pairs (age 6-11, 230 monozygotic) from neighborhoods with above-average levels of family poverty, a risk factor for antisocial behavior. We examined the extent to which correlations between parenting, measured via parent and child report on the Parental Environment Questionnaire, and CU traits reflected genetic versus environmental factors. Then, we tested whether parenting moderated the heritability of CU traits.

resultsIn the context of lower-income neighborhoods, CU traits were moderately to highly heritable (A = 54%) with similar moderate-to-high nonshared environmental influences (E = 46%). Bivariate models revealed that associations between CU traits and warm parenting were genetic (rA = .22) and environmental (rE = .19) in origin, whereas associations between CU traits and harsh parenting were largely genetic in origin (rA = .70). The heritability of CU traits decreased with increasing parental warmth and decreasing harshness.

conclusionsCallous-unemotional traits are both genetic and environmental in origin during middle childhood, but genetic influences are moderated by parenting quality. Parenting may be an important target for interventions, particularly among youth with greater genetic risk.

Indexed as

Conduct DisorderAdolescentAntisocial Personality DisorderChildEmotionsEmpathyHumansParentingGenotype × Environment (G × E) interactionHarshnesstwin modelwarmth

Identifiers

PMID34796486
PMCPMC10049759

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.