Evidence map›Paper›PMID 34796412›Full record

ArticleInternational journal of clinical oncology2022

Neoadjuvant fractionated stereotactic radiotherapy followed by piecemeal resection of brain metastasis: a case series of 20 patients.

Shoichi Deguchi, Koichi Mitsuya, Kazuaki Yasui, Keisuke Kimura, Tsuyoshi Onoe, Hirofumi Ogawa, Hirofumi Asakura, Hideyuki Harada, Nakamasa Hayashi

Open access · hybridAbstract read
In one paragraph

Article in International journal of clinical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. The role of preoperative stereotactic radiotherapy in the management of resectable brain metastases: A systematic review.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Shoichi DeguchiDivision of Neurosurgery, Shizuoka Cancer Center, 1007, Shimo-nagakubo, Naga-izumi, Shizuoka, 411-8777, Japan.
Koichi MitsuyaDivision of Neurosurgery, Shizuoka Cancer Center, 1007, Shimo-nagakubo, Naga-izumi, Shizuoka, 411-8777, Japan. k.mitsuya@scchr.jp.ORCID https://orcid.org/0000-0001-8956-5427
Kazuaki YasuiRadiation and Proton Therapy Center, Shizuoka Cancer Center, Shizuoka, Japan.
Keisuke KimuraDivision of Neurosurgery, Shizuoka Cancer Center, 1007, Shimo-nagakubo, Naga-izumi, Shizuoka, 411-8777, Japan.
Tsuyoshi OnoeRadiation and Proton Therapy Center, Shizuoka Cancer Center, Shizuoka, Japan.
Hirofumi OgawaRadiation and Proton Therapy Center, Shizuoka Cancer Center, Shizuoka, Japan.
Hirofumi AsakuraRadiation and Proton Therapy Center, Shizuoka Cancer Center, Shizuoka, Japan.
Hideyuki HaradaRadiation and Proton Therapy Center, Shizuoka Cancer Center, Shizuoka, Japan.
Nakamasa HayashiDivision of Neurosurgery, Shizuoka Cancer Center, 1007, Shimo-nagakubo, Naga-izumi, Shizuoka, 411-8777, Japan.
Shizuoka Cancer Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe safety and effectiveness of neoadjuvant fractionated stereotactic radiotherapy (FSRT) before piecemeal resection of brain metastasis (BM) remains unknown.

methodsWe retrospectively reviewed 20 consecutive patients with BM who underwent neoadjuvant FSRT followed by piecemeal resection between July 2019 and March 2021. The prescribed dose regimens were as follows: 30 Gy (n = 11) or 35 Gy (n = 9) in five fractions.

resultsThe mean follow-up duration was 7.8 months (range 2.2-22.3). The median age was 67 years (range 51-79). Fourteen patients were male. All patients were symptomatic. All tumors were located in the supratentorial compartment. The median maximum diameter and volume were 3.7 cm (range 2.6-4.9) and 17.6 cm

conclusionsNeoadjuvant FSRT appears to be a safe and effective approach for patients with BM requiring piecemeal resection. A multi-institutional prospective trial is needed.

Indexed as

Brain NeoplasmsRadiosurgeryAgedHumansMaleMiddle AgedNeoadjuvant TherapyNeoplasm Recurrence, LocalProspective StudiesRetrospective StudiesTreatment OutcomeBrain metastasisLeptomeningeal diseaseNeoadjuvant fractionated stereotactic radiotherapyPiecemeal resectionRadiation necrosis

Identifiers

PMID34796412
PMCPMC8882569
OpenAlexW3211928495

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.