Evidence map›Paper›PMID 34796333›Full record

ArticleACS applied polymer materials2021

Bicomponent Cellulose Fibrils and Minerals Afford Wicking Channels Stencil-Printed on Paper for Rapid and Reliable Fluidic Platforms.

Katariina Solin, Maryam Borghei, Monireh Imani, Tero Kämäräinen, Kaisa Kiri, Tapio Mäkelä, Alexey Khakalo, Hannes Orelma, Patrick A C Gane, Orlando J Rojas

Abstract read
In one paragraph

Article in ACS applied polymer materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Particle-Nanofiber Superstructures.Accounts of materials research · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Katariina SolinDepartment of Bioproducts and Biosystems, School of Chemical Engineering, Aalto University, Vuorimiehentie 1, FI-00076 Espoo, Finland.
Maryam BorgheiDepartment of Bioproducts and Biosystems, School of Chemical Engineering, Aalto University, Vuorimiehentie 1, FI-00076 Espoo, Finland.
Monireh ImaniDepartment of Bioproducts and Biosystems, School of Chemical Engineering, Aalto University, Vuorimiehentie 1, FI-00076 Espoo, Finland.ORCID https://orcid.org/0000-0002-0893-8429
Tero KämäräinenDepartment of Bioproducts and Biosystems, School of Chemical Engineering, Aalto University, Vuorimiehentie 1, FI-00076 Espoo, Finland.
Kaisa KiriVTT Technical Research Centre of Finland Ltd., Micronova, Tietotie 3, FI-02150 Espoo, Finland.
Tapio MäkeläVTT Technical Research Centre of Finland Ltd., Micronova, Tietotie 3, FI-02150 Espoo, Finland.
Alexey KhakaloVTT Technical Research Centre of Finland Ltd., Functional Cellulose, Tietotie 4E, FI-02044 Espoo, Finland.ORCID https://orcid.org/0000-0001-7631-9606
Hannes OrelmaVTT Technical Research Centre of Finland Ltd., Functional Cellulose, Tietotie 4E, FI-02044 Espoo, Finland.ORCID https://orcid.org/0000-0001-5070-9542
Patrick A C GaneDepartment of Bioproducts and Biosystems, School of Chemical Engineering, Aalto University, Vuorimiehentie 1, FI-00076 Espoo, Finland.
Orlando J RojasDepartment of Bioproducts and Biosystems, School of Chemical Engineering, Aalto University, Vuorimiehentie 1, FI-00076 Espoo, Finland.ORCID https://orcid.org/0000-0003-4036-4020

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Flexible and easy-to-use microfluidic systems are suitable options for point-of-care diagnostics. Here, we investigate liquid transport in fluidic channels produced by stencil printing on flexible substrates as a reproducible and scalable option for diagnostics and paper-based sensing. Optimal printability and flow profiles were obtained by combining minerals with cellulose fibrils of two different characteristic dimensions, in the nano- and microscales, forming channels with ideal wettability. Biomolecular ligands were easily added by inkjet printing on the channels, which were tested for the simultaneous detection of glucose and proteins. Accurate determination of clinically relevant concentrations was possible from linear calibration, confirming the potential of the introduced paper-based diagnostics. The results indicate the promise of simple but reliable fluidic channels for drug and chemical analyses, chromatographic separation, and quality control.

Identifiers

PMID34796333
PMCPMC8593863

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.