Evidence map›Paper›PMID 34796210›Full record

ArticleFrontiers in cardiovascular medicine2021

Dietary-Induced Elevations of Triglyceride-Rich Lipoproteins Promote Atherosclerosis in the Low-Density Lipoprotein Receptor Knockout Syrian Golden Hamster.

Xiao Lin, Ping Ma, Chun Yang, Jinjie Wang, Kunxiang He, Gonglie Chen, Wei Huang, Jianglin Fan, Xunde Xian, Yuhui Wang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Xiao LinKey Laboratory of Molecular Cardiovascular Science, Ministry of Education, Institute of Cardiovascular Sciences, School of Basic Medical Sciences, Health Science Center, Peking University, Beijing, China.
Ping MaKey Laboratory of Molecular Cardiovascular Science, Ministry of Education, Institute of Cardiovascular Sciences, School of Basic Medical Sciences, Health Science Center, Peking University, Beijing, China.
Chun YangKey Laboratory of Molecular Cardiovascular Science, Ministry of Education, Institute of Cardiovascular Sciences, School of Basic Medical Sciences, Health Science Center, Peking University, Beijing, China.
Jinjie WangKey Laboratory of Molecular Cardiovascular Science, Ministry of Education, Institute of Cardiovascular Sciences, School of Basic Medical Sciences, Health Science Center, Peking University, Beijing, China.
Kunxiang HeKey Laboratory of Molecular Cardiovascular Science, Ministry of Education, Institute of Cardiovascular Sciences, School of Basic Medical Sciences, Health Science Center, Peking University, Beijing, China.
Gonglie ChenKey Laboratory of Molecular Cardiovascular Science, Ministry of Education, Institute of Cardiovascular Sciences, School of Basic Medical Sciences, Health Science Center, Peking University, Beijing, China.
Wei HuangKey Laboratory of Molecular Cardiovascular Science, Ministry of Education, Institute of Cardiovascular Sciences, School of Basic Medical Sciences, Health Science Center, Peking University, Beijing, China.
Jianglin FanDepartment of Molecular Pathology, Graduate School of Medicine, University of Yamanashi, Chuo, Japan.
Xunde XianKey Laboratory of Molecular Cardiovascular Science, Ministry of Education, Institute of Cardiovascular Sciences, School of Basic Medical Sciences, Health Science Center, Peking University, Beijing, China.
Yuhui WangKey Laboratory of Molecular Cardiovascular Science, Ministry of Education, Institute of Cardiovascular Sciences, School of Basic Medical Sciences, Health Science Center, Peking University, Beijing, China.
George LiuKey Laboratory of Molecular Cardiovascular Science, Ministry of Education, Institute of Cardiovascular Sciences, School of Basic Medical Sciences, Health Science Center, Peking University, Beijing, China.
Peking University · CNUniversity of Yamanashi · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Elevated triglycerides are associated with an increased risk of cardiovascular disease (CVD). Therefore, it is very important to understand the metabolism of triglyceride-rich lipoproteins (TRLs) and their atherogenic role in animal models. Using low-density lipoprotein receptor knockout (LDLR

Indexed as

atherosclerosisezetimibelow-density lipoprotein receptorSyrian golden hamstertriglyceride-rich lipoproteins

Identifiers

PMID34796210
PMCPMC8593475
OpenAlexW3209025205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.