Evidence map›Paper›PMID 34796121›Full record

ReviewFrontiers in cellular and infection microbiology2021

First Case of Subcutaneous Mycoses Caused by

Fengming Hu, Chong Wang, Peng Wang, Lei Zhang, Qing Jiang, Abdullah M S Al-Hatmi, Oliver Blechert, Ping Zhan

Open access · goldAbstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Osteomyelitis Caused byTropical medicine and infectious disease · 2025
    Article
  2. Journal of fungi (Basel, Switzerland) · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Fengming HuDepartment of Integrated Chinese and Western Medicine, Dermatology Hospital of Jiangxi Province and Jiangxi Dermatology Institute, Nanchang, China.
Chong WangDermatology Department, Liaocheng People's Hospital, Liaocheng, China.
Peng WangDepartment of Integrated Chinese and Western Medicine, Dermatology Hospital of Jiangxi Province and Jiangxi Dermatology Institute, Nanchang, China.
Lei ZhangDepartment of Integrated Chinese and Western Medicine, Dermatology Hospital of Jiangxi Province and Jiangxi Dermatology Institute, Nanchang, China.
Qing JiangDepartment of Integrated Chinese and Western Medicine, Dermatology Hospital of Jiangxi Province and Jiangxi Dermatology Institute, Nanchang, China.
Abdullah M S Al-HatmiNatural & Medical Sciences Research Center, University of Nizwa, Nizwa, Oman.
Oliver BlechertThe Institute of Clinical Medicine & Dermatology Department, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, China.
Ping ZhanThe Institute of Clinical Medicine & Dermatology Department, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, China.
Jiangxi Provincial People's Hospital · CNLiaocheng People's Hospital · CNNanchang University · CNUniversity of Nizwa · OMXian Yang Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Methods: An 80-year-old female farmer developed extensive plaques and nodules on her left arm within 2 years. Pathological and microbiological examinations identified a new pathological agent, Results: Local barrier damage (i.e., surgery, trauma, and basic dermatosis) and systemic immunodeficiency (i.e., preterm and low birthweight, Crohn's disease, malignant cancer, and chemotherapy) are risk factors for Ustilaginales infection. The D1/D2 and ITS regions are the frequently used loci for identifying the pathogens together with phenotype. Most patients could survive due to antifungal treatment, whereas seven patients died. Amphotericin B, posaconazole, itraconazole, and voriconazole showed good activity against these reported strains, whereas fluconazole, 5-flucytosine, and echinocandins usually showed low susceptibility. Itraconazole had good efficiency for subcutaneous infections. Conclusions: The present case study and literature review reveal that Ustilaginales can be opportunistic pathogenic normally in immunocompromised and barrier damage people. A proper identification of fungi can be crucial for clinical treatment, and more data of antifungal are needed for choice of medication against this kind of infections.

Indexed as

MycosesUstilaginalesAged, 80 and overAntifungal AgentsBasidiomycotaEchinocandinsFluconazoleHumansMicrobial Sensitivity TestsVoriconazoleAntifungal AgentsEchinocandinsFluconazoleVoriconazoleDirkmeiainfectionMoesziomycesPseudozymasubcutaneousUstilaginales

Identifiers

PMID34796121
PMCPMC8593038
OpenAlexW3210944631

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.