Evidence map›Paper›PMID 34796030›Full record

ArticleMultiple sclerosis international2021

Prevalence of Pediatric Onset Multiple Sclerosis in Saudi Arabia.

Reem Bunyan, Ghada Al Towaijri, Hessa Al Otaibi, Abid Kareem, Hussein Algahtani, Mousa Al Mejally, Ali Almubarak, Saad Alrajeh, Edward Cupler, Shireen Qureshi and 11 more

Abstract read
In one paragraph

Article in Multiple sclerosis international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Reem BunyanNeurosciences Center, King Fahd Specialist Hospital (KFSH)-Dammam, Dammam, Saudi Arabia.
Ghada Al TowaijriNeurology Department, King Fahd Medical City Hospital (KFMC), Riyadh, Saudi Arabia.
Hessa Al OtaibiNeurology Department, King Fahd General Hospital-Jeddah, Jeddah, Saudi Arabia.
Abid KareemNeurology Department, King Fahd General Hospital-Al-Madinah, Madinah, Saudi Arabia.
Hussein AlgahtaniNeurology Department, King Abdul-Aziz Medical City, Jeddah, Saudi Arabia.
Mousa Al MejallyNeurology Department, Hera General Hospital, Makkah, Saudi Arabia.
Ali AlmubarakNeurology Department, Qatif Central Hospital, Qatif, Saudi Arabia.
Saad AlrajehNeurology Department, Dr. Sulaiman Al Habib Hospital-Olaya Branch, Riyadh, Saudi Arabia.
Edward CuplerDepartment of Neurosciences, King Faisal Specialist Hospital & Research Center, Jeddah, Saudi Arabia.
Shireen QureshiNeurology Department, Johns Hopkins Aramco Healthcare Company (JHAH), Dhahran, Saudi Arabia.
Sadaga AlawiNeurology Department, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.
Mamdouh KalakatawiNeurology Department, Al Nour Specialized Hospital, Makkah, Saudi Arabia.
Yaser Al MalikCollege of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Shahpar NahrirKing Saud Medical City, Riyadh, Saudi Arabia.
Adel AlhazzaniCollege of Medicine, King Saud University, Riyadh, Saudi Arabia.
Ashraf El-MetwallyCollege of Public Health and Health Informatics, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Sahar ShamiItkan Health Consulting, Riyadh, Saudi Arabia.
Samah IshakItkan Health Consulting, Riyadh, Saudi Arabia.
Hajer AlmudaiheemDeputyship of Therapeutic Affairs, Ministry of Health, Riyadh, Saudi Arabia.
Ahmed Al-JedaiDeputyship of Therapeutic Affairs, Ministry of Health, Riyadh, Saudi Arabia.
Mohammed AlJumahNeurology Department, King Fahd Medical City Hospital (KFMC), Riyadh, Saudi Arabia.ORCID https://orcid.org/0000-0002-9820-9579

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prevalence of multiple sclerosis (MS) appears to be increasing worldwide. However, data on the pediatric onset of MS is lacking, particularly in developing countries.

objectiveThis study is aimed at reporting the current burden of the pediatric onset of MS in the five regions of Saudi Arabia.

methodsThis study used relevant data from the National Saudi MS Registry that was operational between 2015 and 2018. The data on patients with pediatric onset MS from all the hospitals included in the registry was retrospectively analyzed using the age of diagnosis. Patients who were 1-18 years old when diagnosed were included in the analysis.

resultsThe registry included 287 patients with pediatric onset MS, with a mean age of diagnosis at 15.7 (SD: 2.06). 74.2% of the participants were females. For the included hospitals, the estimated prevalence of pediatric MS was at 2.73/100,000 pediatric Saudi population. The prevalence of pediatric MS in the remaining nonparticipant hospitals was then projected taking into account both the size of pediatric population in the Kingdom per region and the number of facilities treating and managing MS in each of the corresponding regions. The overall projected prevalence was found to be 14.33/100,000 Saudi pediatric population.

conclusionTo the best of our knowledge, this study reported the latest epidemiological data of pediatric onset of MS in Saudi Arabia. The current prevalence of MS among the pediatric Saudi population was found to be 2.73/100,000, and the overall projected prevalence was estimated at 14.33/100,000. Our findings were similar to those in other pediatric MS cohorts. Further studies are needed to understand the long-term prognosis, response to treatment, and disease course.

Identifiers

PMID34796030
PMCPMC8595009

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.