Evidence map›Paper›PMID 34795939›Full record

ArticleJournal of thoracic disease2021

Extracorporeal membrane oxygenation in patients with COVID-19: 1-year experience.

Koray Durak, Rashad Zayat, Oliver Grottke, Michael Dreher, Rüdiger Autschbach, Gernot Marx, Nikolaus Marx, Jan Spillner, Sebastian Kalverkamp, Alexander Kersten

Abstract read
In one paragraph

Article in Journal of thoracic disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Koray Durak *Department of Thoracic and Cardiovascular Surgery, RWTH University Hospital Aachen, Aachen, Germany.
Rashad Zayat *Department of Thoracic and Cardiovascular Surgery, RWTH University Hospital Aachen, Aachen, Germany.
Oliver GrottkeDepartment of Anesthesiology, RWTH University Hospital Aachen, Aachen, Germany.
Michael DreherDepartment of Pneumology and Intensive Care Medicine, RWTH University Hospital Aachen, Aachen, Germany.
Rüdiger AutschbachDepartment of Thoracic and Cardiovascular Surgery, RWTH University Hospital Aachen, Aachen, Germany.
Gernot MarxDepartment of Intensive Care and Intermediate Care Medicine, RWTH University Hospital Aachen, Aachen, Germany.
Nikolaus MarxDepartment of Cardiology, Angiology, and Intensive Care, RWTH University Hospital Aachen, Aachen, Germany.
Jan SpillnerDepartment of Thoracic and Cardiovascular Surgery, RWTH University Hospital Aachen, Aachen, Germany.
Sebastian Kalverkamp *Department of Thoracic and Cardiovascular Surgery, RWTH University Hospital Aachen, Aachen, Germany.
Alexander Kersten *Department of Cardiology, Angiology, and Intensive Care, RWTH University Hospital Aachen, Aachen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExtracorporeal membrane oxygenation (ECMO) in patients with coronavirus disease 2019 (COVID-19) showed reasonable outcomes. However, recent studies indicated a negative trend and analysis is needed.

methodsBaseline characteristics, laboratory parameters, and outcomes of ECMO-supported patients with COVID-19 were analyzed in a retrospective single-center study. We included hospital admissions until February 28, 2021; patients were followed until discharge/death. Eventually, we compared data between patients hospitalized before and after September 1, 2020.

resultsMedian age of patients treated with ECMO (n=39) was 56 years; most patients were males (n=28, 72%). Median mechanical ventilation time (prior to ECMO) was 6 days, while the median ECMO duration was 19 days. Overall survival rate was 41%. In the sub-analysis, survival until discharge in the first and second epidemic waves was 53% (n=19) and 30% (n=20), respectively (P=0.2). At baseline, compared with patients of the first wave, those of the second wave had higher median body mass index (28.2

conclusionsECMO-supported patients with COVID-19 had an overall survival rate of 41%. Similar to international registries, we observed less favorable outcomes during the second wave. Further research is needed to confirm this signal and find predictors for mortality.

Indexed as

coronavirus disease 2019 (COVID-19)extracorporeal life support (ECLS)Extracorporeal membrane oxygenation (ECMO)

Identifiers

PMID34795939
PMCPMC8575858

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.