Evidence map›Paper›PMID 34795905›Full record

ArticleCanadian journal of kidney health and disease2021

Percutaneous Versus Surgical Insertion of Peritoneal Dialysis Catheters: A Systematic Review and Meta-Analysis.

Anirudh Agarwal, Reid H Whitlock, Ryan J Bamforth, Thomas W Ferguson, Jenna M Sabourin, Qiming Hu, Sean Armstrong, Claudio Rigatto, Navdeep Tangri, Sara Dunsmore and 1 more

Open access · goldAbstract read
In one paragraph

Article in Canadian journal of kidney health and disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Anirudh AgarwalMax Rady College of Medicine, University of Manitoba, Winnipeg, Canada.
Reid H WhitlockChronic Disease Innovation Centre, Seven Oaks General Hospital, Winnipeg, MB, Canada.ORCID https://orcid.org/0000-0002-7046-0358
Ryan J BamforthChronic Disease Innovation Centre, Seven Oaks General Hospital, Winnipeg, MB, Canada.ORCID https://orcid.org/0000-0002-8316-2325
Thomas W FergusonMax Rady College of Medicine, University of Manitoba, Winnipeg, Canada.ORCID https://orcid.org/0000-0003-1058-943X
Jenna M SabourinMax Rady College of Medicine, University of Manitoba, Winnipeg, Canada.
Qiming HuMax Rady College of Medicine, University of Manitoba, Winnipeg, Canada.
Sean ArmstrongMax Rady College of Medicine, University of Manitoba, Winnipeg, Canada.
Claudio RigattoMax Rady College of Medicine, University of Manitoba, Winnipeg, Canada.ORCID https://orcid.org/0000-0002-8306-8072
Navdeep TangriMax Rady College of Medicine, University of Manitoba, Winnipeg, Canada.
Sara DunsmoreMax Rady College of Medicine, University of Manitoba, Winnipeg, Canada.
Paul KomendaMax Rady College of Medicine, University of Manitoba, Winnipeg, Canada.
Seven Oaks General Hospital · CAUniversity of Manitoba · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHome-based peritoneal dialysis (PD) is an alternative to facility-based hemodialysis and has lower costs and greater freedom for patients with kidney failure. For a patient to undergo PD, a safe and reliable method of accessing the peritoneum is needed. However, different catheter insertion techniques may affect patient health outcomes.

objectiveTo compare the risk of infectious and mechanical complications between surgical (open and laparoscopic) PD catheter insertion and percutaneous catheter insertion.

designSystematic review and meta-analysis.

settingWe searched for observational studies and randomized controlled trials (RCTs) in CENTRAL, EMBASE, MEDLINE, PubMed, and SCOPUS from inception until June 2018. Data were extracted by 2 independent reviewers based on a preformed template. PATIENTS: Adult (aged 18+) patients with kidney failure who underwent a PD catheter insertion procedure. MEASUREMENTS: We analyzed leak, malfunction, and bleed as early complications (occurring within 1 month of catheter insertion). Infectious complications (exit-site infections, tunnel infections, and peritonitis) were presented as both early complications and with the longest duration of follow-up.

methodsRandom effects meta-analyses with the generic inverse variance method to estimate pooled rate ratios and 95% confidence intervals. We quantified heterogeneity by using the I2 statistic for inconsistency and assessed heterogeneity using the χ

resultsTwenty-four studies (22 observational, 2 RCTs) with 3108 patients and 3777 catheter insertions were selected. Data from 2 studies were unable to be extracted and were qualitatively assessed. In the remaining 22 studies, percutaneous insertion was associated with a lower risk of both exit-site infections (risk ratio [RR] = 0.36, 95% confidence interval [CI] = 0.24-0.53, I LIMITATIONS: Lack of consistency in the time periods for the various outcomes reported, risk of bias concerns with respect to population comparability, and the inability to analyze individual component causes of primary nonfunction (catheter obstruction, catheter migration, and leak).

conclusionsOur meta-analysis suggests differences in early infectious complications in favor of percutaneous insertion and no significant differences in mechanical complications compared with surgical insertion. These findings have implications on the direction of PD programs in terms of maximizing operating room resources.

Indexed as

catheterdialysispercutaneousperitonealsurgical

Identifiers

PMID34795905
PMCPMC8593295
OpenAlexW3211534475

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.