Evidence map›Paper›PMID 34795862›Full record

ArticleACS medicinal chemistry letters2021

Evaluation of Specific Binding of [

Fabien Fillesoye, Méziane Ibazizène, Nicolas Marie, Florence Noble, Cécile Perrio

Abstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fabien FillesoyeNormandie Univ, UNICAEN, CEA, CNRS, UMR 6030, LDM-TEP, Cyceron, Boulevard Henri, Becquerel, 14074 Caen, France.
Méziane IbazizèneNormandie Univ, UNICAEN, CEA, CNRS, UMR 6030, LDM-TEP, Cyceron, Boulevard Henri, Becquerel, 14074 Caen, France.
Nicolas MarieUniversité de Paris, CNRS, ERL 3649, Inserm, UMR-S 1124, Pharmacologie et thérapies des addictions, 75006 Paris, France.
Florence NobleUniversité de Paris, CNRS, ERL 3649, Inserm, UMR-S 1124, Pharmacologie et thérapies des addictions, 75006 Paris, France.
Cécile PerrioNormandie Univ, UNICAEN, CEA, CNRS, UMR 6030, LDM-TEP, Cyceron, Boulevard Henri, Becquerel, 14074 Caen, France.ORCID https://orcid.org/0000-0001-6559-3861

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kappa opioid receptor (KOR) PET imaging remains attractive to understand the role of KOR in health and diseases and to help the development of drugs especially for psychiatric disorders such as depression, anxiety, and addiction. The potent and selective KOR antagonist RTI-97 labeled with carbon-11 was previously demonstrated to display specific KOR binding in mouse brain by

Identifiers

PMID34795862
PMCPMC8591749

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.