Evidence map›Paper›PMID 34795858›Full record

ArticleACS medicinal chemistry letters2021

Apoptosis Inducing 1,3,4-Oxadiazole Conjugates of Capsaicin: Their

Fatima Naaz, Faiz Ahmad, Bilal Ahmad Lone, Arif Khan, Kalicharan Sharma, IntzarAli, M ShaharYar, Yuba Raj Pokharel, Syed Shafi

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS medicinal chemistry letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Synthesis and Cytotoxic Activity of 1,2,4-Triazolo-LinkedMolecules (Basel, Switzerland) · 2022
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Fatima NaazDepartment of Chemistry, School of Chemical and Lifescience, Jamia Hamdard, New Delhi-110062, India.
Faiz AhmadFaculty of Life Sciences and Biology, South Asian University, New Delhi-110021, India.
Bilal Ahmad LoneFaculty of Life Sciences and Biology, South Asian University, New Delhi-110021, India.
Arif KhanDepartment of Chemistry, School of Chemical and Lifescience, Jamia Hamdard, New Delhi-110062, India.
Kalicharan SharmaDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi-110062, India.
IntzarAliDepartment of Medical Microbiology, Hamdard Institute of Medical Studies and Research, Jamia Hamdard, New Delhi-110062, India.
M ShaharYarDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi-110062, India.
Yuba Raj PokharelFaculty of Life Sciences and Biology, South Asian University, New Delhi-110021, India.
Syed ShafiDepartment of Chemistry, School of Chemical and Lifescience, Jamia Hamdard, New Delhi-110062, India.ORCID https://orcid.org/0000-0001-7657-0630
Jamia Hamdard · INSouth Asian University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of 1,3,4-oxadiazole tethered capsaicin derivatives was prepared by using one point modification at the vanillyl-hydroxyl group of capsaicin. All the prepared capsaicinoids were evaluated for their antiproliferative activity against NCI-60 human cancer cell lines at 10 μM. Among the compounds tested, compound

Identifiers

PMID34795858
PMCPMC8591727
OpenAlexW3209401448

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.