Evidence map›Paper›PMID 34795671›Full record

ArticleFrontiers in immunology2021

Sustained Post-Developmental T-Bet Expression Is Critical for the Maintenance of Type One Innate Lymphoid Cells

Jan-Hendrik Schroeder, Luke B Roberts, Katrin Meissl, Jonathan W Lo, Dominika Hromadová, Kelly Hayes, Tomasz Zabinski, Emily Read, Catarina Moreira Heliodoro, Rita Reis and 5 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Transcriptional control of ILC identity.Frontiers in immunology · 2023
    Review
  9. Article
  10. ILC3: a case of conflicted identity.Frontiers in immunology · 2023
    Review
  11. Review
  12. Article
  13. Innate Lymphoid Cells and Intestinal Inflammatory Disorders.International journal of molecular sciences · 2022
    Review
  14. Review
  15. Review
  16. Review
  17. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Jan-Hendrik SchroederSchool of Immunology and Microbial Sciences, King's College London, London, United Kingdom.
Luke B RobertsSchool of Immunology and Microbial Sciences, King's College London, London, United Kingdom.
Katrin MeisslInstitute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Vienna, Austria.
Jonathan W LoSchool of Immunology and Microbial Sciences, King's College London, London, United Kingdom.
Dominika HromadováInstitute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Vienna, Austria.
Kelly HayesSchool of Biological Sciences, Faculty of Biology, Medicine and Health, Division of Infection, Immunity and Respiratory Medicine, University of Manchester, Manchester, United Kingdom.
Tomasz ZabinskiSchool of Immunology and Microbial Sciences, King's College London, London, United Kingdom.
Emily ReadSchool of Immunology and Microbial Sciences, King's College London, London, United Kingdom.
Catarina Moreira HeliodoroSchool of Immunology and Microbial Sciences, King's College London, London, United Kingdom.
Rita ReisSchool of Immunology and Microbial Sciences, King's College London, London, United Kingdom.
Jane K HowardDepartment of Diabetes, School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College, London, United Kingdom.
Richard K GrencisSchool of Biological Sciences, Faculty of Biology, Medicine and Health, Division of Infection, Immunity and Respiratory Medicine, University of Manchester, Manchester, United Kingdom.
Joana F NevesSchool of Immunology and Microbial Sciences, King's College London, London, United Kingdom.
Birgit StroblInstitute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Vienna, Austria.
Graham M LordSchool of Immunology and Microbial Sciences, King's College London, London, United Kingdom.
King's College London · GBUniversity of Veterinary Medicine Vienna · ATUniversity of Manchester · GBImperial College London · GBWellcome Trust · GB

Funding

Department of HealthMedical Research Council MR/K002996/1Medical Research Council MR/M003493/1Medical Research Council MR/R024812/1Wellcome Trust 091009Wellcome Trust 210661/Z/18/ZWellcome Trust 215027/Z/18/Z
6 · The paper itself

Abstract

Innate lymphoid cells (ILC) play a significant role in the intestinal immune response and T-bet

Indexed as

AnimalsCitrobacter rodentiumColitisDextran SulfateEnterobacteriaceae InfectionsFemaleImmunity, InnateIntestinal MucosaLymphocytesMaleMiceMice, Inbred BALB CMice, Inbred C57BLMice, TransgenicSTAT1 Transcription FactorSTAT4 Transcription FactorDextran SulfateStat1 protein, mouseSTAT1 Transcription FactorStat4 protein, mouseSTAT4 Transcription FactorTamoxifenT-bet Transcription FactorT-Box Domain ProteinsILCsinnate lymphoid cellsintestinal inflammationmucosal homeostasis 4T-bet

Identifiers

PMID34795671
PMCPMC8594445
OpenAlexW3208598130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.