ArticleNature immunology2021
Homeostatic IL-13 in healthy skin directs dendritic cell differentiation to promote T
Erratum issuedOpen access · greenAbstract read
In one paragraph
Article in Nature immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 68 papers.
0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
68 citing papers in PubMed, 125 citations in OpenAlex.
- The IL-33/ST2 pathway to modulate the inflammatory microenvironment: A new therapeutic target in chronic obstructive pulmonary disease.Biochemistry and biophysics reports · 2026Review
- Dysbiosis-induced expansion of AXL-positive inflammatory type 3 dendritic cells triggers preclinical autoimmunity.Nature immunology · 2026Article
- Distinct postnatal trajectories of mouse dendritic epidermal T cells and Langerhans cells independent of microbiota.Science advances · 2026Article
- Interleukin-4-producing type 2 innate lymphoid cells in the lymph node promote proallergic Tfh13 cell differentiation.Immunity · 2026Article
- Group 2 innate lymphoid cells program pulmonary adaptive immunity via granulocyte-macrophage colony-stimulating factor.The Journal of allergy and clinical immunology · 2026Article
- Review
- Immunological dynamics of the epididymis: from experimental insights to clinical translation.Reproduction & fertility · 2026Review
- Enhanced Alarmin Secretion Exacerbates Neutrophil Extracellular Trap (NET) Formation in Active Psoriasis: Implication of IL-33 and TSLP in Driving NET Formation, Inflammation and Oxidative Stress in Psoriasis.Antioxidants (Basel, Switzerland) · 2026Article
- Skeletal muscle as a dynamic immunological niche for vaccination.Frontiers in immunology · 2026Review
- RAG1 deficiency durably alters dermal group 2 innate lymphoid cells and modifies contact hypersensitivity.Frontiers in immunology · 2026Article
- Basophils activate splenic B cells and dendritic cells via IL-13 signaling in acute traumatic brain injury.Journal of neuroinflammation · 2025Article
- Biologic Therapies Targeting Type 2 Signaling in Atopic Dermatitis: A Comparative Review of Structural and Thermodynamic Differences in Mechanism of Action.The Journal of investigative dermatology · 2025Review
- Peptide ES15-1 derived from Haemonchus contortus promotes goat Th17 response by regulating the STAT3/RORγt pathway.Veterinary research · 2025Article
- Ontogenetic Diversification of Type 2 Conventional Dendritic Cells in the Bone Marrow: A Central Logic for Peripheral Immunity.Immunological reviews · 2025Review
- Oral and Skin Sensitisation to Peanut Show Different Immunological Features in Brown Norway Rats.Scandinavian journal of immunology · 2025Article
- Functional Specialization and Collaboration of cDC2 Subsets in CD4+ T Cell Priming and Differentiation.Immunological reviews · 2025Review
- Dendritic Cells: Origin, Classification, Development, Biological Functions, and Therapeutic Potential.MedComm · 2025Review
- Antigen-presenting cells as arbiters of mucosal tolerance and immunity.Nature immunology · 2025Review
- Integrative epidemiology and immunotranscriptomics uncover a risk and potential mechanism for cutaneous lymphoma unmasking or progression with dupilumab therapy.The Journal of allergy and clinical immunology · 2025Article
- Tissue-Resident Th2 Cells in Type 2 Immunity and Allergic Diseases.Immunological reviews · 2025Review
8 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Commented on by
- Erratum issued
Authors and funding
25 authors at 7 institutions in 6 countries.
Johannes U MayerMalaghan Institute of Medical Research, Wellington, New Zealand.ORCID http://orcid.org/0000-0001-6225-7803
Kerry L HilliganMalaghan Institute of Medical Research, Wellington, New Zealand.
Jodie S ChandlerMalaghan Institute of Medical Research, Wellington, New Zealand.
David A EcclesMalaghan Institute of Medical Research, Wellington, New Zealand.ORCID http://orcid.org/0000-0003-4634-4995
Samuel I OldMalaghan Institute of Medical Research, Wellington, New Zealand.ORCID http://orcid.org/0000-0003-1245-4459
Rita G DominguesLydia Becker Institute of Immunology and Inflammation, Manchester Collaborative Centre for Inflammation Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
Jianping YangMalaghan Institute of Medical Research, Wellington, New Zealand.
Greta R WebbMalaghan Institute of Medical Research, Wellington, New Zealand.ORCID http://orcid.org/0000-0003-0348-3119
Luis Munoz-ErazoMalaghan Institute of Medical Research, Wellington, New Zealand.ORCID http://orcid.org/0000-0003-4202-1515
Evelyn J HydeMalaghan Institute of Medical Research, Wellington, New Zealand.
Kirsty A WakelinMalaghan Institute of Medical Research, Wellington, New Zealand.
Shiau-Choot TangMalaghan Institute of Medical Research, Wellington, New Zealand.
Sally C ChappellMalaghan Institute of Medical Research, Wellington, New Zealand.
Sventja von DaakeMalaghan Institute of Medical Research, Wellington, New Zealand.
Frank BrombacherInternational Centre for Genetic Engineering and Biotechnology (ICGEB), Cape Town component & Institute of Infectious Diseases and Molecular Medicine (IDM), Division of Immunology, Health Science Faculty, University of Cape Town, Cape Town, South Africa.
Charles R MackayInfection and Immunity Program, Monash Biomedicine Discovery Institute, Monash University, Melbourne, VIC, Australia.ORCID http://orcid.org/0000-0002-6338-7340
Alan SherImmunobiology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID http://orcid.org/0000-0001-7053-2895
Roxane TussiwandDepartment of Biomedicine, University of Basel, Basel, Switzerland.ORCID http://orcid.org/0000-0002-1712-868X
Lisa M ConnorMalaghan Institute of Medical Research, Wellington, New Zealand.
David Gallego-OrtegaThe Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.
Dragana JankovicImmunoparasitology Unit, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID http://orcid.org/0000-0001-7360-1809
Graham Le GrosMalaghan Institute of Medical Research, Wellington, New Zealand.ORCID http://orcid.org/0000-0002-5721-0442
Matthew R HepworthLydia Becker Institute of Immunology and Inflammation, Manchester Collaborative Centre for Inflammation Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.ORCID http://orcid.org/0000-0002-9613-7858
Olivier Lamiable *Malaghan Institute of Medical Research, Wellington, New Zealand.ORCID http://orcid.org/0000-0001-7571-9253
Franca Ronchese *Malaghan Institute of Medical Research, Wellington, New Zealand. fronchese@malaghan.org.nz.ORCID http://orcid.org/0000-0001-5835-8230
Malaghan Institute of Medical Research · NZNational Institutes of Health · USManchester Academic Health Science Centre · GBAustralian Regenerative Medicine Institute · AUUniversity of Basel · CHUniversity of Cape Town · ZAUniversity of Technology Sydney · AU
Funding
Wellcome Trust 105644/Z/14/Z
Abstract
The signals driving the adaptation of type 2 dendritic cells (DC2s) to diverse peripheral environments remain mostly undefined. We show that differentiation of CD11b
Indexed as
Cell CommunicationCell DifferentiationAllergensAnimalsCD11b AntigenCells, CulturedDatabases, GeneticHumansInterleukin-13Langerhans CellsMiceMice, Inbred BALB CMice, Inbred C57BLMice, KnockoutPhenotypeSignal TransductionAllergensCD11b AntigenIL13 protein, humanInterleukin-13ITGAM protein, humanItgam protein, mouseSTAT6 protein, humanStat6 protein, mouseSTAT6 Transcription Factor
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.