Evidence map›Paper›PMID 34795411›Full record

ArticleActa pharmacologica Sinica2022

ADT-OH inhibits malignant melanoma metastasis in mice via suppressing CSE/CBS and FAK/Paxillin signaling pathway.

Fang-Fang Cai, Huang-Ru Xu, Shi-Hui Yu, Ping Li, Yan-Yan Lu, Jia Chen, Zhi-Qian Bi, Hui-Song Sun, Jian Cheng, Hong-Qin Zhuang and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Acta pharmacologica Sinica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. A universal consuming endogenous HBioactive materials · 2027
    Article
  2. Article
  3. Sulfide regulation and catabolism in health and disease.Signal transduction and targeted therapy · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Hydrogen Sulfide Suppresses Skin Fibroblast ProliferationOxidative medicine and cellular longevity · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Fang-Fang Cai *The State Key Laboratory of Pharmaceutical Biotechnology, College of Life Sciences, Nanjing University, Nanjing, 210008, China.
Huang-Ru Xu *The State Key Laboratory of Pharmaceutical Biotechnology, College of Life Sciences, Nanjing University, Nanjing, 210008, China.
Shi-Hui YuThe State Key Laboratory of Pharmaceutical Biotechnology, College of Life Sciences, Nanjing University, Nanjing, 210008, China.
Ping LiThe State Key Laboratory of Pharmaceutical Biotechnology, College of Life Sciences, Nanjing University, Nanjing, 210008, China.
Yan-Yan LuThe State Key Laboratory of Pharmaceutical Biotechnology, College of Life Sciences, Nanjing University, Nanjing, 210008, China.
Jia ChenThe State Key Laboratory of Pharmaceutical Biotechnology, College of Life Sciences, Nanjing University, Nanjing, 210008, China.
Zhi-Qian BiThe State Key Laboratory of Pharmaceutical Biotechnology, College of Life Sciences, Nanjing University, Nanjing, 210008, China.
Hui-Song SunThe State Key Laboratory of Pharmaceutical Biotechnology, College of Life Sciences, Nanjing University, Nanjing, 210008, China.
Jian ChengInstitute of Neuroscience, Soochow University, Suzhou, 215031, China. jiancheng8@hotmail.com.
Hong-Qin ZhuangThe State Key Laboratory of Pharmaceutical Biotechnology, College of Life Sciences, Nanjing University, Nanjing, 210008, China. hqzhuang@nju.edu.cn.
Zi-Chun HuaThe State Key Laboratory of Pharmaceutical Biotechnology, College of Life Sciences, Nanjing University, Nanjing, 210008, China. hzc1117@nju.edu.cn.
Nanjing University · CNChina Pharmaceutical University · CNSoochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogen sulfide (H

Indexed as

MelanomaThionesAnimalsCell Line, TumorCell MovementChromatography, LiquidCutaneous Malignant MelanomaFocal Adhesion Kinase 1MiceNeoplasm InvasivenessNeoplasm MetastasisPaxillinSignal TransductionSkin NeoplasmsTandem Mass Spectrometry5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thioneFocal Adhesion Kinase 1PaxillinPtk2 protein, mouseThionesADT-OHCSE/CBSEMTFAKhydrogen sulfidemelanomapaxillintumor metastasis

Identifiers

PMID34795411
PMCPMC9253130
OpenAlexW3212969804

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.