Evidence map›Paper›PMID 34795394›Full record

ArticleNature biomedical engineering2023

Rapid adaptation of brain-computer interfaces to new neuronal ensembles or participants via generative modelling.

Shixian Wen, Allen Yin, Tommaso Furlanello, M G Perich, L E Miller, Laurent Itti

Abstract read
In one paragraph

Article in Nature biomedical engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Neural Decoding for Intracortical Brain-Computer Interfaces.Cyborg and bionic systems (Washington, D.C.) · 2023
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shixian WenUniversity of Southern California, Los Angeles, CA, USA. shixianw@usc.edu.ORCID 0000-0003-2104-235X
Allen YinFacebook, Menlo Park, CA, USA.
Tommaso FurlanelloUniversity of Southern California, Los Angeles, CA, USA.
M G PerichUniversity of Geneva, Geneva, Switzerland.ORCID 0000-0001-9800-2386
L E MillerNorthwestern University, Chicago, IL, USA.ORCID 0000-0001-8675-7140
Laurent IttiUniversity of Southern California, Los Angeles, CA, USA. itti@usc.edu.ORCID 0000-0002-0168-2977

Funding

Primate model of an intracortically controlled FES prostR01NS053603 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KENNEDY, ANN KATHRYN, MILLER, LEE · 2006 to 2021
$7.1M
PATHOPHYSIOLOGY AND REHABILITATION OF NEURAL DYSFUNCTIONT32HD007418 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Levi John Hargrove · 1992 to 2026
$6.5M
The representation of uncertainty in the sensorimotor systemR01NS074044 · NINDS · REHABILITATION INSTITUTE OF CHICAGO D/B/A SHIRLEY RYAN ABILITYLAB · PI KORDING, KONRAD P., MILLER, LEE · 2011 to 2015
$1.6M
Motor Cortical Function During Motor Learning with a Brain-Machine InterfaceF31NS092356 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PERICH, MATTHEW GEORGE · 2015 to 2017
$93k
NICHD NIH HHS T32 HD007418NINDS NIH HHS F31 NS092356NINDS NIH HHS R01 NS053603NINDS NIH HHS R01 NS074044
6 · The paper itself

Abstract

For brain-computer interfaces (BCIs), obtaining sufficient training data for algorithms that map neural signals onto actions can be difficult, expensive or even impossible. Here we report the development and use of a generative model-a model that synthesizes a virtually unlimited number of new data distributions from a learned data distribution-that learns mappings between hand kinematics and the associated neural spike trains. The generative spike-train synthesizer is trained on data from one recording session with a monkey performing a reaching task and can be rapidly adapted to new sessions or monkeys by using limited additional neural data. We show that the model can be adapted to synthesize new spike trains, accelerating the training and improving the generalization of BCI decoders. The approach is fully data-driven, and hence, applicable to applications of BCIs beyond motor control.

Indexed as

Brain-Computer InterfacesAlgorithmsBiomechanical PhenomenaHumansNeurons

Identifiers

PMID34795394
PMCPMC9114171

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.