Evidence map›Paper›PMID 34795365›Full record

ArticleScientific reports2021

Deep learning-based histopathological segmentation for whole slide images of colorectal cancer in a compressed domain.

Hyeongsub Kim, Hongjoon Yoon, Nishant Thakur, Gyoyeon Hwang, Eun Jung Lee, Chulhong Kim, Yosep Chong

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

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  12. Deep learning-based computed tomographic image super-resolution via wavelet embedding.Radiation physics and chemistry (Oxford, England : 1993) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hyeongsub KimDepartments of Electrical Engineering, Creative IT Engineering, Mechanical Engineering, School of Interdisciplinary Bioscience and Bioengineering, Medical Device Innovation Center, and Graduate School of Artificial Intelligence, Pohang University of Science and Technology (POSTECH), Pohang, 37674, South Korea.
Hongjoon YoonDeepnoid Inc., Seoul, 08376, South Korea.
Nishant ThakurDepartment of Hospital Pathology, The Catholic University of Korea, College of Medicine, Uijeongbu St. Mary's Hospital, Seoul, South Korea.
Gyoyeon HwangDepartment of Hospital Pathology, The Catholic University of Korea, College of Medicine, Yeouido St. Mary's Hospital, Seoul, South Korea.
Eun Jung LeeDepartment of Hospital Pathology, The Catholic University of Korea, College of Medicine, Yeouido St. Mary's Hospital, Seoul, South Korea.
Chulhong KimDepartments of Electrical Engineering, Creative IT Engineering, Mechanical Engineering, School of Interdisciplinary Bioscience and Bioengineering, Medical Device Innovation Center, and Graduate School of Artificial Intelligence, Pohang University of Science and Technology (POSTECH), Pohang, 37674, South Korea. chulhong@postech.edu.
Yosep ChongDepartment of Hospital Pathology, The Catholic University of Korea, College of Medicine, Uijeongbu St. Mary's Hospital, Seoul, South Korea. ychong@catholic.ac.kr.

Funding

Ministry of Science and ICT, South Korea 2020M3H2A1078045the Ministry of Education 2018R1D1A1A02050922
6 · The paper itself

Abstract

Automatic pattern recognition using deep learning techniques has become increasingly important. Unfortunately, due to limited system memory, general preprocessing methods for high-resolution images in the spatial domain can lose important data information such as high-frequency information and the region of interest. To overcome these limitations, we propose an image segmentation approach in the compressed domain based on principal component analysis (PCA) and discrete wavelet transform (DWT). After inference for each tile using neural networks, a whole prediction image was reconstructed by wavelet weighted ensemble (WWE) based on inverse discrete wavelet transform (IDWT). The training and validation were performed using 351 colorectal biopsy specimens, which were pathologically confirmed by two pathologists. For 39 test datasets, the average Dice score, the pixel accuracy, and the Jaccard score were 0.804 ± 0.125, 0.957 ± 0.025, and 0.690 ± 0.174, respectively. We can train the networks for the high-resolution image with the large region of interest compared to the result in the low-resolution and the small region of interest in the spatial domain. The average Dice score, pixel accuracy, and Jaccard score are significantly increased by 2.7%, 0.9%, and 2.7%, respectively. We believe that our approach has great potential for accurate diagnosis.

Indexed as

Deep LearningAlgorithmsColorectal NeoplasmsComputer GraphicsComputersHumansImage Processing, Computer-AssistedMachine LearningNeural Networks, ComputerPredictive Value of TestsPrincipal Component AnalysisProbabilityReproducibility of ResultsSoftwareUser-Computer InterfaceWavelet Analysis

Identifiers

PMID34795365
PMCPMC8602325

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.