Evidence map›Paper›PMID 34795353›Full record

ArticleScientific reports2021

Right atrium size in the general population.

Karsten Keller, Christoph Sinning, Andreas Schulz, Claus Jünger, Volker H Schmitt, Omar Hahad, Tanja Zeller, Manfred Beutel, Norbert Pfeiffer, Konstantin Strauch and 6 more

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Bedside Admittance Control of a Dual-Segment Soft Robot for Catheter-Based Interventions.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Echocardiographic evaluation of the right atrial size and function: Relevance for clinical practice.American heart journal plus : cardiology research and practice · 2023
    Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Karsten KellerDepartment of Cardiology, Cardiology I, University Medical Center, Johannes Gutenberg University Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany. Karsten.Keller@unimedizin-mainz.de.
Christoph SinningDepartment of General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany.
Andreas SchulzPreventive Cardiology and Preventive Medicine - Department of Cardiology, University Medical Center, Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.
Claus JüngerDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center, Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.
Volker H SchmittDepartment of Cardiology, Cardiology I, University Medical Center, Johannes Gutenberg University Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany.
Omar HahadDepartment of Cardiology, Cardiology I, University Medical Center, Johannes Gutenberg University Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany.
Tanja ZellerDepartment of General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany.
Manfred BeutelDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center, Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.
Norbert PfeifferDepartment of Ophthalmology, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany.
Konstantin StrauchInstitute for Medical Biometrics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University Mainz, Obere Zahlbacher Str. 69, 55131, Mainz, Germany.
Stefan BlankenbergDepartment of General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany.
Karl J LacknerGerman Center for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Mainz, Germany.
Jürgen H ProchaskaDepartment of Cardiology, Cardiology I, University Medical Center, Johannes Gutenberg University Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany.
Eberhard SchulzDepartment of Cardiology, Cardiology I, University Medical Center, Johannes Gutenberg University Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany.
Thomas Münzel *Department of Cardiology, Cardiology I, University Medical Center, Johannes Gutenberg University Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany.
Philipp S Wild *Department of Cardiology, Cardiology I, University Medical Center, Johannes Gutenberg University Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany.

Funding

DIASyM research core BMBF 161L0217AFederal Ministry of Education and Research BMBF 01EO1503
6 · The paper itself

Abstract

Echocardiography is the most common routine cardiac imaging method. Nevertheless, only few data about sex-specific reference limits for right atrium (RA) dimensions are available. Transthoracic echocardiographic RA measurements were studied in 9511 participants of the Gutenberg-Health-Study. A reference sample of 1942 cardiovascular healthy subjects without chronic obstructive pulmonary disease was defined. We assessed RA dimensions and sex-specific reference limits were defined using the 95th percentile of the reference sample. Results showed sex-specific differences with larger RA dimensions in men that were attenuated by standardization for body-height. RA-volume was 20.2 ml/m in women (5th-95th: 12.7-30.4 ml/m) and 26.1 ml/m in men (5th-95th: 16.0-40.5 ml/m). Multivariable regressions identified body-mass-index (BMI), coronary artery disease (CAD), chronic heart failure (CHF) and atrial fibrillation (AF) as independent key correlates of RA-volume in both sexes. All-cause mortality after median follow-up-period of 10.7 (9.81/11.6) years was higher in individuals who had RA volume/height outside the 95% reference limit (HR 1.70 [95%CI 1.29-2.23], P = 0.00014)). Based on a large community-based sample, we present sex-specific reference-values for RA dimensions normalized for height. RA-volume varies with BMI, CHF, CAD and AF in both sexes. Individuals with RA-volume outside the reference limit had a 1.7-fold higher mortality than those within reference limits.

Indexed as

AdultAgedAtrial FibrillationBody Mass IndexCoronary Artery DiseaseEchocardiographyFemaleGermanyHeart AtriaHeart FailureHumansMaleMiddle AgedMultivariate AnalysisReference ValuesRisk Factors

Identifiers

PMID34795353
PMCPMC8602329

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.