Evidence map›Paper›PMID 34795291›Full record

ArticleNPJ microgravity2021

Altered sleep spindles and slow waves during space shuttle missions.

Dominik P Koller, Vida Kasanin, Erin E Flynn-Evans, Jason P Sullivan, Derk-Jan Dijk, Charles A Czeisler, Laura K Barger

Open access · goldAbstract read
In one paragraph

Article in NPJ microgravity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. [Effects of Extreme Environments on Human Sleep].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Review
  6. Article
  7. Review
  8. Frontiers in immunology · 2024
    Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Dominik P KollerAdvanced Concepts Team, European Space Agency, ESTEC, Noordwijk, The Netherlands. dominik.koller@charite.de.
Vida KasaninAdvanced Concepts Team, European Space Agency, ESTEC, Noordwijk, The Netherlands.ORCID http://orcid.org/0000-0002-1817-7782
Erin E Flynn-EvansFatigue Countermeasures Laboratory, Human Systems Integration Division, Exploration Technology Directorate, NASA Ames Research Center, Moffett Field, CA, USA.
Jason P SullivanDivision of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Derk-Jan DijkSurrey Sleep Research Centre, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
Charles A CzeislerDivision of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0002-7408-1849
Laura K BargerDivision of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0001-8547-7331
Brigham and Women's Hospital · USEuropean Space Research and Technology Centre · NLAmes Research Center · USUniversity of Surrey · GB

Funding

ACL HHS R01OH011773
6 · The paper itself

Abstract

Sleep deficiencies and associated performance decrements are common among astronauts during spaceflight missions. Previously, sleep in space was analyzed with a focus on global measures while the intricate structure of sleep oscillations remains largely unexplored. This study extends previous findings by analyzing how spaceflight affects characteristics of sleep spindles and slow waves, two sleep oscillations associated with sleep quality and quantity, in four astronauts before, during and after two Space Shuttle missions. Analysis of these oscillations revealed significantly increased fast spindle density, elevated slow spindle frequency, and decreased slow wave amplitude in space compared to on Earth. These results reflect sleep characteristics during spaceflight on a finer electrophysiological scale and provide an opportunity for further research on sleep in space.

Identifiers

PMID34795291
PMCPMC8602337
OpenAlexW3212042145

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.