Evidence map›Paper›PMID 34794947›Full record

ArticleAJNR. American journal of neuroradiology2022

Transcranial Doppler Velocities and Angiographic Vasospasm after SAH: A Diagnostic Accuracy Study.

T E Darsaut, M B Keough, A M Chan, B Farzin, J M Findlay, M M Chow, M Chagnon, J Zehr, G Gevry, J Raymond

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
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  5. Article
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  7. Article
  8. Reply.AJNR. American journal of neuroradiology · 2022
    Article
  9. Article
  10. Transcranial Doppler Arterial Pressure Gradient Is Associated With Delayed Infarction After Subarachnoid Hemorrhage.Journal of neuroimaging : official journal of the American Society of Neuroimaging
    Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

T E DarsautFrom the Division of Neurosurgery (T.E.D., M.B.K., A.M.C., J.M.F., M.M.C.), Department of Surgery, University of Alberta Hospital, Mackenzie Health Sciences Centre, Edmonton, Alberta, Canada.ORCID 0000-0003-4662-1550
M B KeoughFrom the Division of Neurosurgery (T.E.D., M.B.K., A.M.C., J.M.F., M.M.C.), Department of Surgery, University of Alberta Hospital, Mackenzie Health Sciences Centre, Edmonton, Alberta, Canada.ORCID 0000-0001-5361-3327
A M ChanFrom the Division of Neurosurgery (T.E.D., M.B.K., A.M.C., J.M.F., M.M.C.), Department of Surgery, University of Alberta Hospital, Mackenzie Health Sciences Centre, Edmonton, Alberta, Canada.ORCID 0000-0002-3884-9902
B FarzinDepartment of Radiology (B.F., G.G., J.R.), Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.ORCID 0000-0003-0420-1005
J M FindlayFrom the Division of Neurosurgery (T.E.D., M.B.K., A.M.C., J.M.F., M.M.C.), Department of Surgery, University of Alberta Hospital, Mackenzie Health Sciences Centre, Edmonton, Alberta, Canada.ORCID 0000-0002-4842-3905
M M ChowFrom the Division of Neurosurgery (T.E.D., M.B.K., A.M.C., J.M.F., M.M.C.), Department of Surgery, University of Alberta Hospital, Mackenzie Health Sciences Centre, Edmonton, Alberta, Canada.ORCID 0000-0002-8074-3511
M ChagnonDepartment of Mathematics and Statistics (M.C., J.Z.), Pavillon André-Aisenstadt, Montreal, Quebec, Canada.ORCID 0000-0002-2291-9566
J ZehrDepartment of Mathematics and Statistics (M.C., J.Z.), Pavillon André-Aisenstadt, Montreal, Quebec, Canada.ORCID 0000-0002-8295-4590
G GevryDepartment of Radiology (B.F., G.G., J.R.), Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.ORCID 0000-0003-1982-3480
J RaymondDepartment of Radiology (B.F., G.G., J.R.), Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada jean.raymond@Umontreal.ca.ORCID 0000-0003-1978-4274
Health Sciences Centre · CACentre Hospitalier de l’Université de Montréal · CAMcGill University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeAfter aneurysmal SAH, transcranial Doppler is commonly used to monitor cerebral vasospasm. The diagnostic accuracy of transcranial Doppler flow velocity values in detecting angiographic vasospasm in patients requiring urgent endovascular intervention has not been established. MATERIALS AND

methodsWe performed a retrospective analysis of a consecutive series of patients with aneurysmal SAH who underwent transcranial Doppler (index test) within 24 hours of conventional angiography (reference test). The judgment of 33%, 50%, and 66% degree of vessel narrowing on angiography was independently established by multiple neuroendovascular clinicians. Vessel-specific per-segment and per-patient transcranial Doppler velocities were studied using receiver operating characteristic curves, the Youden index, and minimal acceptable sensitivity models. Optimal mean flow-velocity thresholds were explored to calculate sensitivity and specificity using a per-patient judgment of vasospasm of at least 50% angiographic narrowing in any large arterial segment except A1.

resultsIn 221 patients, vasospasm was found in 15%, 8%, and 4% of arteries when the degree of reference angiographic luminal narrowing was 33%, 50%, and 66%, respectively. Mean flow velocities were significantly higher in vasospastic segments (

conclusionsIn this study, a threshold transcranial Doppler mean flow-velocity value that would accurately diagnose ≥50% angiographic vasospasm remained elusive.

Indexed as

Subarachnoid HemorrhageVasospasm, IntracranialBlood Flow VelocityCerebral AngiographyCerebrovascular CirculationHumansRetrospective StudiesUltrasonography, Doppler, Transcranial

Identifiers

PMID34794947
PMCPMC8757545
OpenAlexW3213721712

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.