Evidence map›Paper›PMID 34794616›Full record

ArticleThe American journal of cardiology2021

Gaps and Disparities in Primary Prevention Statin Prescription During Outpatient Care.

Gil Metser, Corey Bradley, Nathalie Moise, Nadia Liyanage-Don, Ian Kronish, Siqin Ye

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in The American journal of cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 38 citations in OpenAlex.

  1. Trial
  2. Prevalence of statin utilization in cancer survivors in a family medicine clinic.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  3. Reducing Sex Disparities in Statin Therapy Among Female Veterans With Type 2 Diabetes and/or Cardiovascular Disease.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2025
    Article
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  8. Learning health system linchpins: information exchange and a common data model.Journal of the American Medical Informatics Association : JAMIA · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Gil MetserDivision of General Internal Medicine, Department of Medicine, Columbia University Medical Center and New York-Presbyterian Hospital, New York, New York. Electronic address: gim9056@nyp.org.
Corey BradleyDivision of Cardiology, Department of Medicine, Columbia University Medical Center and New York-Presbyterian Hospital, New York, New York.
Nathalie MoiseDivision of General Internal Medicine, Department of Medicine, Columbia University Medical Center and New York-Presbyterian Hospital, New York, New York.
Nadia Liyanage-DonDivision of General Internal Medicine, Department of Medicine, Columbia University Medical Center and New York-Presbyterian Hospital, New York, New York.
Ian KronishDivision of General Internal Medicine, Department of Medicine, Columbia University Medical Center and New York-Presbyterian Hospital, New York, New York.
Siqin YeDivision of Cardiology, Department of Medicine, Columbia University Medical Center and New York-Presbyterian Hospital, New York, New York.
NewYork–Presbyterian Hospital · US

Funding

Patient health information preference and statin therapyK23HL121144 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI YE, SIQIN · 2014 to 2018
$784k
NHLBI NIH HHS K23 HL121144
6 · The paper itself

Abstract

The 2018 American College of Cardiology/American Heart Association Guideline on the Management of Blood Cholesterol recommends statin therapy for eligible patients to reduce the risk of atherosclerotic cardiovascular disease (ASCVD). We extracted electronic health record data for patients with at least one primary care or cardiology visit between October 2018 and January 2020 at an urban, academic medical center in New York City. Clinical and demographic data were used to identify patients eligible for primary prevention statin therapy. Statin prescription status was extracted from the electronic health record, and multivariate logistic regression was used to assess the association between statin prescription and age, gender, race, ethnicity, and other clinical and demographic covariables. In 7,550 patients eligible for primary prevention statin therapy, 3,994 (52.9%) were prescribed statins on at least 1 visit. Statin prescription was highest in patients with diabetes mellitus (73.6%) and with a 10-year ASCVD risk ≥20% (60.6%) and was lowest for those with a 10-year ASCVD risk between 5% and 7.5% (18.7%). Compared with those never prescribed statins, patients prescribed statins were less likely to be women, mainly driven by lower statin prescription rates for women with diabetes. In a fully adjusted model, women remained less likely to be prescribed statin therapy (adjusted odds ratios 0.79, 95% confidence interval 0.71 to 0.88). In conclusion, primary prevention statin therapy remains underutilized.

Indexed as

AgedAmbulatory CareCardiovascular DiseasesDrug PrescriptionsElectronic Health RecordsFemaleHealthcare DisparitiesHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMaleMiddle AgedPrescription DrugsPrimary PreventionRetrospective StudiesHydroxymethylglutaryl-CoA Reductase InhibitorsPrescription Drugs

Identifiers

PMID34794616
PMCPMC8607804
OpenAlexW3214247857

What OpenQuestion holds

Texttitle and abstract
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.