ArticleBMC genomics2021
Genome-wide characterization and analysis of WRKY transcription factors in Panax ginseng.
Article in BMC genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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23 citing papers in PubMed, 62 citations in OpenAlex.
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- PnWRKY38-PnSUS1 axis regulates the biosynthesis ofHorticulture research · 2026Article
- Melatonin-inducedFrontiers in plant science · 2026Article
- Genome-wide identification and analysis of YTH gene family and its response to MeJA and salt treatment in Panax ginseng C. A. Meyer.BMC plant biology · 2025Article
- A Heat-Shock Transcription Factor inInternational journal of molecular sciences · 2025Article
- Genome-wide identification and transcriptional expression profiles of the transcription factor WRKY in Gentiana macrophylla.Molecular biology reports · 2025Article
- The transcription factor ClWRKY61 interacts with ClLEA55 to enhance salt tolerance in watermelon.Horticulture research · 2025Article
- Genome-wide identification and characterization of WRKYs family involved in responses to Cylindrocarpon destructans in Panax notoginseng.BMC genomics · 2025Article
- Identification, characterization, and expression analysis of WRKY transcription factors inFrontiers in plant science · 2025Article
- Light Regulated CoWRKY15 Acts on CoSQS Promoter to Promote Squalene Synthesis inInternational journal of molecular sciences · 2024Article
- Genome-Wide Identification and Analysis of the Aux/IAA Gene Family inInternational journal of molecular sciences · 2024Article
- Genomic characterization of WRKY transcription factors related to secoiridoid biosynthesis in Gentiana macrophylla.BMC plant biology · 2024Article
- Genome-wide profiling of WRKY genes involved in flavonoid biosynthesis inFrontiers in plant science · 2024Article
- Gene Expression and Interaction Analysis ofPlants (Basel, Switzerland) · 2023Article
- Multi-algorithm cooperation research of WRKY genes under nitrogen stress in Panax notoginseng.Protoplasma · 2023Article
- Multilayered regulation of secondary metabolism in medicinal plants.Molecular horticulture · 2023Review
- Transcriptome-Wide Integrated Analysis of thePlants (Basel, Switzerland) · 2023Article
- Genome-Wide Identification and Expression Analysis of WRKY Gene Family inInternational journal of molecular sciences · 2023Article
- Genome-Wide Identification, Evolutionary and Functional Analyses of WRKY Family Members inGenes · 2023Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
backgroundPanax ginseng is a well-known medicinal plant worldwide. As an herbal medicine, ginseng is also known for its long lifecycle, which can reach several decades. WRKY proteins play regulatory roles in many aspects of biological processes in plants, such as responses to biotic or abiotic stress, plant development, and adaptation to environmental challenges. Genome-wide analyses of WRKY genes in P. ginseng have not been reported.
resultsIn this study, 137 PgWRKY genes were identified from the ginseng genome. Phylogenetic analysis showed that the PgWRKYs could be clustered into three primary groups and five subgroups. Most of the PgWRKY gene promoters contained several kinds of hormone- and stress-related cis-regulatory elements. The expression patterns of PgWRKY genes in 14 different tissues were analyzed based on the available public RNA-seq data. The responses of the PgWRKY genes to heat, cold, salt and drought treatment were also investigated. Most of the PgWRKY genes were expressed differently after heat treatment, and expression trends changed significantly under drought and cold treatment but only slightly under salt treatment. The coexpression analysis of PgWRKY genes with the ginsenoside biosynthesis pathway genes identified 11 PgWRKYs that may have a potential regulatory role in the biosynthesis process of ginsenoside.
conclusionsThis work provides insights into the evolution, modulation and distribution of the WRKY gene family in ginseng and extends our knowledge of the molecular basis along with modulatory mechanisms of WRKY transcription factors in ginsenoside biosynthesis.
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