Evidence map›Paper›PMID 34794321›Full record

ArticleCancer control : journal of the Moffitt Cancer Center

Evaluating Incidence, Location, and Predictors of Positive Surgical Margin Among Chinese Men Undergoing Robot-Assisted Radical Prostatectomy.

Wugong Qu, Shuanbao Yu, Jin Tao, Biao Dong, Yafeng Fan, Haopeng Du, Haotian Deng, Junxiao Liu, Xuepei Zhang

Open access · goldAbstract read
In one paragraph

Article in Cancer control : journal of the Moffitt Cancer Center. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Development of preoperative nomograms to predict the risk of overall and multifocal positive surgical margin after radical prostatectomy.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Wugong QuDepartment of Urology, The First Affiliated Hospital of 191599Zhengzhou University, Zhengzhou, China.
Shuanbao YuDepartment of Urology, The First Affiliated Hospital of 191599Zhengzhou University, Zhengzhou, China.
Jin TaoDepartment of Urology, The First Affiliated Hospital of 191599Zhengzhou University, Zhengzhou, China.
Biao DongDepartment of Urology, The First Affiliated Hospital of 191599Zhengzhou University, Zhengzhou, China.
Yafeng FanDepartment of Urology, The First Affiliated Hospital of 191599Zhengzhou University, Zhengzhou, China.
Haopeng DuDepartment of Urology, The First Affiliated Hospital of 191599Zhengzhou University, Zhengzhou, China.
Haotian DengDepartment of Urology, The First Affiliated Hospital of 191599Zhengzhou University, Zhengzhou, China.
Junxiao LiuDepartment of Urology, The First Affiliated Hospital of 191599Zhengzhou University, Zhengzhou, China.
Xuepei ZhangDepartment of Urology, The First Affiliated Hospital of 191599Zhengzhou University, Zhengzhou, China.ORCID https://orcid.org/0000-0003-0919-5871
First Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the incidence and locations of positive surgical margin (PSM) among Chinese men undergoing RARP and identify the preoperative predictors for PSM.

methodsWe retrospectively identified 393 patients who underwent RARP according to inclusion criteria by single surgeon in our hospital. PSM was defined as the presence of cancer adjacent to inked surface of the specimen and categorized into four groups based on locations: apex, posterolateral, base, and multifocal. Logistic regression analysis was performed to identify the predictors of overall and location-specific PSM.

resultsThe overall PSM rate was 133/393 (34%). The PSM rates for pT2, pT3, and pT4 stage were 63/278 (23%), 50/89 (56%), and 20/26 (77%), respectively. The estimated rates for apical, posterolateral, basal, and multifocal PSM were 8%, 4%, 7%, and 14%, respectively. In univariate analysis, overall PSM related to tPSA, f/tPSA, percentage of positive needles, and Gleason score. Multifocal PSM correlated with smoking history, drinking history, tPSA, f/tPSA, percentage of positive needles, and Gleason score. In multivariate analysis, percentage of positive needles reminded the only independent predictor for overall (OR = 10.5, 95% CI: 2.58-44.4) and basal PSM (OR = 24.0, 95% CI: 3.22-179.4). The f/tPSA (OR = 2.59, 95% CI: 2.18-5.71) and percentage of positive needles (OR = 31.0, 95% CI: 3.17-303) were independent risk factors for multifocal PSM.

conclusionThe multifocal sites were the most common location of positive surgical margin, followed by apical and basal sites among Chinese patients undergoing RARP. The percentage of positive needles was an independent predictor for overall, basal, and multifocal PSM.

Indexed as

Margins of ExcisionAgedChinaComorbidityHumansIncidenceLogistic ModelsMaleMiddle AgedNeoplasm GradingNeoplasm Recurrence, LocalProstatectomyProstatic NeoplasmsRetrospective StudiesRisk FactorsRobotic Surgical Procedurespositive surgical marginprostate cancerradical prostatectomyrobot

Identifiers

PMID34794321
PMCPMC8645302
OpenAlexW3212129927

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.