Evidence map›Paper›PMID 34794320›Full record

ArticleCirculation research2022

Renal AT

Brandon A Kemp, Nancy L Howell, John J Gildea, Susanna R Keller, David L Brautigan, Robert M Carey

Open access · greenAbstract read
In one paragraph

Article in Circulation research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. G protein-coupled receptor kinases in hypertension: physiology, pathogenesis, and therapeutic targets.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Review
  3. Review
  4. Article
  5. Review
  6. The Angiotensin ATPharmacological reviews · 2022
    Review
  7. Article
  8. Review
  9. The NaFrontiers in physiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Brandon A KempDivision of Endocrinology and Metabolism, Department of Medicine (BAK, NLH, SRK, RMC), University of Virginia School of Medicine, Charlottesville, VA.ORCID 0000-0002-0609-3557
Nancy L HowellDivision of Endocrinology and Metabolism, Department of Medicine (BAK, NLH, SRK, RMC), University of Virginia School of Medicine, Charlottesville, VA.
John J GildeaDepartments of Pathology (JJG) and Microbiology, University of Virginia School of Medicine, Charlottesville, VA.
Susanna R KellerDivision of Endocrinology and Metabolism, Department of Medicine (BAK, NLH, SRK, RMC), University of Virginia School of Medicine, Charlottesville, VA.
David L BrautiganImmunology & Cancer Biology (DLB), University of Virginia School of Medicine, Charlottesville, VA.
Robert M CareyDivision of Endocrinology and Metabolism, Department of Medicine (BAK, NLH, SRK, RMC), University of Virginia School of Medicine, Charlottesville, VA.ORCID 0000-0001-7238-7396
University of Virginia · US

Funding

Renal AT2 Receptors in HypertensionR01HL128189 · NHLBI · UNIVERSITY OF VIRGINIA · PI KELLER, SUSANNA R · 2016 to 2024
$5.0M
Multiscale Modeling of Myelodysplastic SyndromesR01HL128173 · NHLBI · VIRGINIA COMMONWEALTH UNIVERSITY · PI COREY, SETH JOEL, KIMMEL, MAREK · 2015 to 2019
$3.8M
NHLBI NIH HHS R01 HL128173NHLBI NIH HHS R01 HL128189
6 · The paper itself

Abstract

backgroundHow signals from activated angiotensin type-2 receptors (AT METHODS AND

resultsIn Wistar-Kyoto rats, direct renal interstitial administration of selective AT

conclusionsIn renal proximal tubule cells of Wistar-Kyoto rats, PP2A is activated and PP2A subunits AB55αC are recruited to C-21-activated AT

Indexed as

NatriuresisAnimalsCells, CulturedCyclic GMPFemaleKidneyProtein Phosphatase 2RatsRats, WistarReceptor, Angiotensin, Type 2SodiumCyclic GMPProtein Phosphatase 2Receptor, Angiotensin, Type 2Sodiumangiotensinscyclic GMPhypertensionkidneynatriuresis

Identifiers

PMID34794320
PMCPMC8741733
OpenAlexW3212684055

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.