Evidence map›Paper›PMID 34793687›Full record

Trial reportAnnals of the American Thoracic Society2022

Biomarkers to Predict Response to Inhaled Corticosteroids and Long-Acting Muscarinic Antagonists in Adolescents and Adults with Mild Persistent Asthma.

Jerry A Krishnan, Stephen C Lazarus, Kathryn V Blake, Christine A Sorkness, Ronina Covar, Anne-Marie Dyer, Jason E Lang, Njira L Lugogo, David T Mauger, Michael E Wechsler and 6 more

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Annals of the American Thoracic Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Questions in Mild Asthma: An Official American Thoracic Society Research Statement.American journal of respiratory and critical care medicine · 2023
    Article
  5. Promising treatment biomarkers in asthma.Frontiers in drug safety and regulation · 2023
    Review
  6. Allergic Asthma in the Era of Personalized Medicine.Journal of personalized medicine · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 12 institutions in 1 country.

Jerry A KrishnanUniversity of Illinois at Chicago, Chicago, Illinois.ORCID 0000-0001-5525-4778
Stephen C LazarusUniversity of California, San Francisco, California.
Kathryn V BlakeNemours Children's Health, Jacksonville, Florida.ORCID 0000-0001-9959-8572
Christine A SorknessUniversity of Wisconsin, Madison, Wisconsin.
Ronina CovarNational Jewish Health, Denver, Colorado.
Anne-Marie DyerPennsylvania State University, Hershey, Pennsylvania.
Jason E LangDuke University School of Medicine, Durham, North Carolina.
Njira L LugogoUniversity of Michigan, Ann Arbor, Michigan.
David T MaugerPennsylvania State University, Hershey, Pennsylvania.
Michael E WechslerNational Jewish Health, Denver, Colorado.
Sally E WenzelUniversity of Pittsburgh, Pittsburgh, Pennsylvania.
Juan Carlos CardetUniversity of South Florida, Tampa, Florida.
Mario CastroUniversity of Kansas School of Medicine, Kansas City, Kansas.
Elliot IsraelHarvard Medical School Brigham & Women's Hospital, Boston, Massachusetts; and.
Wanda PhipatanakulBoston Children's Hospital, Boston, Massachusetts.
Tonya S KingPennsylvania State University, Hershey, Pennsylvania.
Pennsylvania State University · USNational Jewish Health · USBoston Children's Hospital · USBrigham and Women's Hospital · USDuke University · USUniversity of California, San Francisco · USUniversity of Illinois Chicago · USUniversity of Kansas · USUniversity of Michigan · USUniversity of Pittsburgh · USUniversity of South Florida · USUniversity of Wisconsin–Madison · US

Funding

Data Coordinating Center for the NHLBI Asthma Network (AsthmaNet)U10HL098115 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI MAUGER, DAVID T. · 2009 to 2015
$57.6M
Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Clinical and Translational Science Collaborative of ClevelandUL1TR000439 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$50.0M
Colorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0M
Clinical and Translational Science Collaborative of ClevelandUL1TR002548 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI MCCOMSEY, GRACE A · 2018 to 2022
$35.5M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
AsthmaNet: Brigham and Women's Hospital & Children's Hospital BostonU10HL098102 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ISRAEL, ELLIOT, PHIPATANAKUL, WANDA · 2009 to 2015
$5.5M
Clinical Centers for the NHLBI Asthma Network (AsthmaNet)U10HL098075 · NHLBI · NATIONAL JEWISH HEALTH · PI SZEFLER, STANLEY J., WECHSLER, MICHAEL E · 2009 to 2015
$5.1M
AsthmaNet: UW-Madison Clinical and Translational Research CenterU10HL098090 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI LEMANSKE, ROBERT F, SORKNESS, CHRISTINE ANNE · 2009 to 2015
$4.8M
UCSF AsthmaNet Clinical CenterU10HL098107 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CABANA, MICHAEL D, LAZARUS, STEPHEN C · 2009 to 2015
$4.8M
AsthmaNet: Phenotypic Influences on Asthma TreatmentsU10HL098177 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HOLGUIN, FERNANDO, WENZEL, SALLY E · 2009 to 2015
$4.7M
Arizona/Duke Clinical Center for AsthmaNetU10HL098112 · NHLBI · UNIVERSITY OF ARIZONA · PI KRAFT, MONICA, MARTINEZ, FERNANDO D · 2009 to 2015
$4.7M
NCATS NIH HHS UL1 TR000439NCATS NIH HHS UL1 TR000454NCATS NIH HHS UL1 TR001082NCATS NIH HHS UL1 TR001422NCATS NIH HHS UL1 TR002548NHLBI NIH HHS U10 HL098075NHLBI NIH HHS U10 HL098090NHLBI NIH HHS U10 HL098096NHLBI NIH HHS U10 HL098098NHLBI NIH HHS U10 HL098102NHLBI NIH HHS U10 HL098103NHLBI NIH HHS U10 HL098107NHLBI NIH HHS U10 HL098112NHLBI NIH HHS U10 HL098115NHLBI NIH HHS U10 HL098177NIAID NIH HHS K23 AI125785NIH HHS HL098075NIH HHS HL098090NIH HHS HL098096NIH HHS HL098098NIH HHS HL098102NIH HHS HL098103NIH HHS HL098107NIH HHS HL098112NIH HHS HL098115NIH HHS HL098177NIH HHS TR000439NIH HHS TR000454NIH HHS TR001082NIH HHS TR001422NIH HHS TR991872
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AsthmaMuscarinic AntagonistsAdministration, InhalationAdolescentAdrenal Cortex HormonesAdultBiomarkersHumansInfantProspective StudiesAdrenal Cortex HormonesBiomarkersMuscarinic Antagonistsblood eosinophilsclinical trialfractional exhaled nitric oxideprecision medicinesputum eosinophils

Identifiers

PMID34793687
PMCPMC8937224
OpenAlexW3213914620

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.