Evidence map›Paper›PMID 34793565›Full record

ArticlePloS one2021

Percutaneous transhepatic drainage is safe and effective in biliary obstruction-A single-center experience of 599 patients.

Bálint Kokas, Attila Szijártó, Nelli Farkas, Miklós Ujváry, Szabolcs Móri, Adél Kalocsai, Ákos Szücs

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Percutaneous Transhepatic Biliary Intervention for The Management of Malignant Hilar Biliary Obstruction.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025
    Article
  5. Comparison of endoscopic retrograde cholangiopancreatography drainageWorld journal of gastrointestinal pharmacology and therapeutics · 2025
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Bálint KokasDepartment of Surgery, Transplantation and Gastroenterology, Semmelweis University, Budapest, Hungary.
Attila SzijártóDepartment of Surgery, Transplantation and Gastroenterology, Semmelweis University, Budapest, Hungary.
Nelli FarkasInstitute of Bioanalysis, University of Pécs, Pécs, Hungary.
Miklós UjváryDepartment of Surgery, Transplantation and Gastroenterology, Semmelweis University, Budapest, Hungary.
Szabolcs MóriDepartment of Surgery, Transplantation and Gastroenterology, Semmelweis University, Budapest, Hungary.
Adél KalocsaiDepartment of Surgery, Transplantation and Gastroenterology, Semmelweis University, Budapest, Hungary.
Ákos SzücsDepartment of Surgery, Transplantation and Gastroenterology, Semmelweis University, Budapest, Hungary.
Semmelweis University · HUUniversity of Pecs · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHistorically, surgical bilioenteric bypass was the only treatment option for extrahepatic bile duct obstruction, but with technological advancements, percutaneous transhepatic drainage (PTD) and endoscopic solutions were introduced as a less invasive alternative. Endoscopic methods may lead to a decreasing indication of PTD in the future, but today it is still the standard treatment method, especially in hilar obstructions.

methodsIn our retrospective data analysis, we assessed technical success rate, reintervention rate, morbidity, mortality, and the learning curve of patients treated with PTD over 12 years in a tertiary referral center.

results599 patients were treated with 615 percutaneous interventions. 94.5% (566/599) technical success rate; 2.7% (16/599) reintervention rate were achieved. 111 minor and 22 major complications occurred including 1 case of death. In perihilar obstruction, cholangitis were significantly more frequent in cases where endoscopic retrograde cholangiopancreatography had also been performed prior to PTD compared to PTD alone, with 39 (18.2%) and 15 (10.5%) occurrences, respectively. DISCUSSION: The results and especially the excellent success rates demonstrate that PTD is safe and effective, and it is appropriate for first choice in the treatment algorithm of perihilar stenosis. Ultimately, we concluded that PTD should be performed in experienced centers to achieve low mortality, morbidity, and high success rates.

Indexed as

AgedCholangiopancreatography, Endoscopic RetrogradeCholangitisCholestasis, ExtrahepaticConstriction, PathologicDrainageFemaleHumansMaleRetrospective Studies

Identifiers

PMID34793565
PMCPMC8601527
OpenAlexW3213750703

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.