Evidence map›Paper›PMID 34793523›Full record

ArticlePloS one2021

Using large-scale respondent driven sampling to monitor the end of an HIV epidemic among persons who inject drugs in Hai Phong, Viet Nam.

Don C Des Jarlais, Kamyar Arasteh, Duong Thi Huong, Khuat Thi Hai Oanh, Jonathan P Feelemyer, Pham Minh Khue, Hoang Thi Giang, Nham Thi Tuyet Thanh, Vu Hai Vinh, Sao Mai Le and 8 more

Registry-linked trialAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07121296 (Screen, Treat and Retain People With Primary Meth Use Disorder at MMT Clinics), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07121296 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Screen, Treat and Retain People With Primary Meth Use Disorder at MMT Clinics

TypeinterventionalSponsorHanoi Medical UniversityRan2025 to 2025Enrolled60ConditionsMethamphetamine Use DisorderArmsContingency management for substance use, Contingency management for attendance, Group-based Matrix counseling, Individual-based Matrix counseling
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Don C Des JarlaisNew York University School of Global Public Health, New York, NY, United States of America.ORCID 0000-0002-0157-8168
Kamyar ArastehNew York University School of Global Public Health, New York, NY, United States of America.
Duong Thi HuongHaiphong University of Medicine and Pharmacy, Haiphong, Vietnam.
Khuat Thi Hai OanhSupporting Community Development Initiatives, Hanoi, Vietnam.
Jonathan P FeelemyerNew York University School of Global Public Health, New York, NY, United States of America.
Pham Minh KhueHaiphong University of Medicine and Pharmacy, Haiphong, Vietnam.ORCID 0000-0003-2974-3484
Hoang Thi GiangHaiphong University of Medicine and Pharmacy, Haiphong, Vietnam.
Nham Thi Tuyet ThanhSupporting Community Development Initiatives, Hanoi, Vietnam.
Vu Hai VinhDept of Infectious and Tropical diseases, Viet Tiep Hospital, Haiphong, Vietnam.
Sao Mai LeHaiphong University of Medicine and Pharmacy, Haiphong, Vietnam.
Roselyne ValloPathogenèses and control of chronic and emerging infections, University of Montpellier, Inserm, Etablissement Français du Sang, University of Antilles, Montpellier, France.ORCID 0000-0002-2447-6754
Catherine QuilletPathogenèses and control of chronic and emerging infections, University of Montpellier, Inserm, Etablissement Français du Sang, University of Antilles, Montpellier, France.
Delphine RapoudPathogenèses and control of chronic and emerging infections, University of Montpellier, Inserm, Etablissement Français du Sang, University of Antilles, Montpellier, France.
Laurent MichelPierre Nicole Center, French Red Cross, CESP/Inserrm 1018, Paris, France.
Didier LaureillardPathogenèses and control of chronic and emerging infections, University of Montpellier, Inserm, Etablissement Français du Sang, University of Antilles, Montpellier, France.
Jean Pierre MolesPathogenèses and control of chronic and emerging infections, University of Montpellier, Inserm, Etablissement Français du Sang, University of Antilles, Montpellier, France.ORCID 0000-0002-6863-6350
Nicolas NagotPathogenèses and control of chronic and emerging infections, University of Montpellier, Inserm, Etablissement Français du Sang, University of Antilles, Montpellier, France.
DRIVE Study Team

Funding

DRIVE (DRug use and blood-borne Infections in ViEtnam): Combined prevention and care to end the HIV epidemic among people who inject drugs in Haiphong, Viet NamR01DA041978 · NIDA · NEW YORK UNIVERSITY · PI DES JARLAIS, DON C · 2016 to 2020
$4.9M
NIDA NIH HHS R01 DA041978
6 · The paper itself

Abstract

aimsTo describe the use of large-scale respondent driven sampling (RDS) surveys to demonstrate the "end of an HIV epidemic" (HIV incidence < 0.5/100 person-years) among persons who inject drugs (PWID) in a middle-income country. Large sample sizes are needed to convincingly demonstrate very low incidence rates.

methods4 large surveys (Ns approximately 1500 each) were conducted among PWID in Hai Phong, Vietnam in 2016-2019. Respondent driven sampling (RDS) with a modification to add snowball sampling was used for recruiting participants. HIV incidence was measured through recency testing, repeat participants across multiple surveys and in a cohort study of PWID recruited from the surveys. RDS analytics (time to equilibria and homophilies for major variables) were used to assess similarities/differences in RDS only versus RDS plus snowball recruiting. Characteristics were compared among respondents recruited through standard RDS recruitment versus through snowball sampling. An overall assessment of the robustness of RDS to modification was made when adding a snowball sampling recruitment.

resultsRDS recruiting was very efficient in the first 5 weeks of each survey with approximately 180 respondents recruited per week. Recruiting then slowed considerably, and snowball sampling (permitting an individual respondent to recruit large numbers of new respondents) was added to the existing RDS recruiting. This led to recruiting within 13-14 weeks of 1383, 1451, 1444 and 1268 respondents, close to the target of 1500 respondents/survey. Comparisons of participants recruited through standard RDS method and respondents recruited through snowball methods showed very few significant differences. RDS analytics (quickly reaching equilibria, low homophilies) were favorable for both RDS recruited and total numbers of participants in each survey. DRug use and Infections in ViEtnam (DRIVE) methods have now been officially adopted in other provinces.

conclusionsRDS appears to be quite robust with respect to adding a modest number of participants recruited through snowball sampling. Large sample sizes can provide compelling evidence for "ending an HIV epidemic" to policy makers in a PWID population in a middle income country setting.

Indexed as

EpidemicsEpidemiological MonitoringAdultCohort StudiesFemaleHIV InfectionsHumansMaleSample SizeSampling StudiesSubstance Abuse, IntravenousVietnam

Identifiers

PMID34793523
PMCPMC8601441

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.