Evidence map›Paper›PMID 34792856›Full record

ArticleJournal of applied clinical medical physics2022

A system for real-time monitoring of breath-hold via assessment of internal anatomy in tangential breast radiotherapy.

Elena N Vasina, Peter Greer, David Thwaites, Tomas Kron, Joerg Lehmann

Abstract read
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Article in Journal of applied clinical medical physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Elena N VasinaSchool of Information and Physical Sciences, University of Newcastle, Newcastle, New South Wales, Australia.
Peter GreerSchool of Information and Physical Sciences, University of Newcastle, Newcastle, New South Wales, Australia.
David ThwaitesInstitute of Medical Physics, School of Physics, University of Sydney, Sydney, New South Wales, Australia.
Tomas KronPeter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Joerg LehmannSchool of Information and Physical Sciences, University of Newcastle, Newcastle, New South Wales, Australia.

Funding

National Health and Medical Research Council 1147533
6 · The paper itself

Abstract

The deep inspiration breath-hold (DIBH) technique assists in sparing the heart, lungs, and liver during breast radiotherapy (RT). The quality of DIBH is currently assessed via surrogates which correlate to varying degrees with the patient's internal anatomy. Since modern linacs are equipped with an electronic portal imaging device (EPID), images of the irradiated anatomy streamed from EPIDs and analyzed in real time could significantly improve assessment of the quality of DIBH. A system has been developed to quantify the quality of DIBH during tangential breast RT by analyzing the "beam's eye view" images of the treatment fields. The system measures the lung depth (LD) and the distance from the breast surface to the posterior tangential radiation field edge (skin distance, SD) at three user-defined locations. LD and SD measured in real time in EPID images of two RT phantoms showing different geometrical characteristics of their chest wall regions (computed tomography dose index [CTDI] and "END-TO-END" stereotactic body radiation therapy [E2E SBRT]) were compared with ground truth displacements provided by a precision motion platform. Performance of the new system was evaluated via static and dynamic (sine wave motion) measurements of LD and SD, covering clinical situations with stable and unstable breath-hold. The accuracy and precision of the system were calculated as the mean and standard deviation of the differences between the ground truth and measured values. The accuracy of the static measurements of LD and SD for the CTDI phantom was 0.31 (1.09) mm [mean (standard deviation)] and -0.10 (0.14) mm, respectively. The accuracy of the static measurements for E2E SBRT phantom was 0.01 (0.18) mm and 0.05 (0.08) mm. The accuracy of the dynamic LD and SD measurements for the CTDI phantom was -0.50 (1.18) mm and 0.01 (0.12) mm, respectively. The accuracy of the dynamic measurements for E2E SBRT phantom was -0.03 (0.19) mm and 0.01 (0.11) mm.

Indexed as

Breast NeoplasmsTomography, X-Ray ComputedBreath HoldingFemaleHeartHumansLungRadiotherapy DosageRadiotherapy Planning, Computer-Assistedcentral lung distancedeep inspiration breath-hold (DIBH)EPIDlung depthmonitoring of internal anatomyreal-time portal imagingtangential breast radiotherapy

Identifiers

PMID34792856
PMCPMC8803293

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.