ArticleJournal of applied clinical medical physics2022
Evaluation of parameters affecting gamma passing rate in patient-specific QAs for multiple brain lesions IMRS treatments using ray-station treatment planning system.
Article in Journal of applied clinical medical physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed, 13 citations in OpenAlex.
- Using machine learning to predict gamma passing rate in volumetric-modulated arc therapy treatment plans.Journal of applied clinical medical physics · 2023Trial
- Influence of dose calculation algorithms on the helical diode array using volumetric-modulated arc therapy for small targets.Journal of applied clinical medical physics · 2024Article
- Assessing the sensitivity and suitability of a range of detectors for SIMT PSQA.Journal of applied clinical medical physics · 2024Article
- Evaluating the Hounsfield unit assignment and dose differences between CT-based standard and deep learning-based synthetic CT images for MRI-only radiation therapy of the head and neck.Journal of applied clinical medical physics · 2024Article
- Evaluation of parameters affecting gamma passing rate in patient-specific QAs for multiple brain lesions IMRS treatments using ray-station treatment planning system.Journal of applied clinical medical physics · 2022Article
- Assessment of Calculation Grid Size Impact on Plan Quality and Gamma Evaluation Metrics in Intracranial Stereotactic Radiotherapy.Journal of medical physicsArticle
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Authors and funding
4 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposeUsing intensity-modulated radiosurgery (IMRS) with single isocenter for the treatment of multiple brain lesions has gained acceptance in recent years. One of the challenges of this technique is conducting a patient-specific quality assurance (QA), involving accurate gamma passing rate (GPR) calculations for small and wide spread-out targets. We evaluated effects of parameters such as dose grid and energy on GPR using our clinical IMRS plans.
methodsTen patients with total of 40 volumetric modulated arc therapy (VMAT) plans were created in Raystation (V.8A) treatment planning system (TPS) for the Varian Edge Linac using 6 and 10 flattening filter-free (FFF) beams and planned dose grids of 1 mm and 2 mm resulting in four plans with 6-10 targets per patient. All parameters and objectives except dose grid and energy were kept the same in all plans. Next, patient-specific QAs were measured evaluating GPR with 10% threshold, 3%/3 mm objective, and an acceptance criterion of 95%. Modulation factors (MF) and confidence intervals were calculated. Two modes of measurements, standard density (SD) and high density (HD), were used.
resultsGenerally, plans computed with 1 mm dose grid have higher GPRs than those with 2 mm dose grid for both energies used. The GPRs of 6 FFF plans were higher than those of 10 FFF plans. GPR showed no noticeable difference between HD and SD measurements. Negative correlation between MF and GPR was observed. The HD pass rates fall within the confidence interval of SD.
conclusionCalculated dose grid should be less than or equal to one-third of distance to agreement, thus 1 mm planned dose grid is recommended to reduce artifacts in gamma calculation. GPR of SD and HD measurement modes is almost the same, which indicates that SD mode is clinically preferable for performing patient-specific QAs. According to our results, using 6 FFF beams with 1 mm planned dose grid is more accurate and reliable for dose calculation of IMRS plans.
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