Evidence map›Paper›PMID 34792785›Full record

SynthesisAdvances in therapy2022

Effects of High-Intensity Interval Training on Pulmonary Function and Exercise Capacity in Individuals with Chronic Obstructive Pulmonary Disease: A Meta-Analysis and Systematic Review.

Min Gao, Yangxi Huang, Qianyi Wang, Kouying Liu, Guozhen Sun

Erratum issued 2 registry-linked trialsAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Advances in therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 2 registered trials, which are not on this map. Cited by 20 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 5 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05779046 nacompletednot on this map

The Acute Effect of High Intensity Interval Exercise on Respiratory Function and Rhinitis Symptoms in Patients With Allergic Rhinitis

TypeinterventionalSponsorChulalongkorn UniversityRan2022 to 2022Enrolled12ConditionsAllergic RhinitisArmsHIT 1:1, HIT 1:2
NCT06322446 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Effects of a Strength Exercise Program on Muscular Health in People With CF Treated With Modulators of the Cystic Fibrosis Transmembrane Conductance Regulator Receptor (CFTR)

TypeinterventionalSponsorUniversidad Politecnica de MadridRan2024 to 2026Enrolled48ConditionsCystic FibrosisArmsExercise
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 5 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Exercise and pulmonary embolism: a systematic review of exercise safety, feasibility and effectiveness.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Feasibility and Tolerance of High-Intensity Interval Training in Adults With Cystic Fibrosis.Archives of rehabilitation research and clinical translation · 2026
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Exercise Prescription Training in Chronic Obstructive Pulmonary Disease: Benefits and Mechanisms.International journal of chronic obstructive pulmonary disease · 2025
    Review
  15. Article
  16. Article
  17. Review
  18. Exercising with Asthma: A Slow Burn or a Quick HIIT?The journal of allergy and clinical immunology. In practice · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Min Gao *The Nursing School, Nanjing Medical University, Nanjing, China.
Yangxi Huang *The Nursing School, Nanjing Medical University, Nanjing, China.
Qianyi WangJiangyin People's Hospital of Jiangsu Province, Jiangyin, China.
Kouying LiuThe Nursing School, Nanjing Medical University, Nanjing, China.
Guozhen SunCardiology Department of the First Affiliated Hospital of Nanjing Medical University, The Nursing School, Nanjing Medical University, Nanjing, China. gzsun100@njmu.edu.cn.ORCID http://orcid.org/0000-0003-0445-7633
Nanjing Medical University · CNJiangsu Province Hospital · CNJiangyin People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study aimed to examine the effectiveness of high-intensity interval training (HIIT) on pulmonary function and exercise capacity in individuals with chronic obstructive pulmonary disease (COPD).

methodsTen databases (PubMed, the Cochrane Library, Web of Science, EMBASE, MEDLINE, CINAHL, CNKI, Wanfang, Weipu, and CBM) were searched for relevant articles published from inception to 30 June 2020. Studies were included if they were randomized controlled trials (RCTs) comparing a HIIT group with usual care or other training groups. Quality was assessed using the Physiotherapy Evidence Database (PEDro) scale, and the overall quality of evidence was assessed using the GRADE approach. The primary outcomes were peak VO

resultsTwelve articles (689 patients) were included. HIIT was shown to have a positive effect on exercise capacity (peak WR, 6MWD), pulmonary function (FEV

conclusionsHIIT could improve pulmonary function, exercise capacity, and quality of life but may not decrease dyspnea in patients with COPD. It can be recommended as a safe and effective exercise modality in rehabilitation programs. Given that the overall results were based on a limited number of studies with significant heterogeneity and some of the results were based on low GRADE rating evidence, more high-quality, larger sample size, multicenter, and long-term follow-up RCTs are needed to confirm the clinical efficacy of HIIT in patients with COPD. PROSPERO REGISTRATION: CRD42020165897.

Indexed as

High-Intensity Interval TrainingPulmonary Disease, Chronic ObstructiveDyspneaExercise ToleranceHumansMulticenter Studies as TopicQuality of LifeChronic obstructive pulmonary diseaseExercise capacityHigh-intensity interval exercisePulmonary function

Identifiers

PMID34792785
OpenAlexW3213580417

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.