ArticleSleep & breathing = Schlaf & Atmung2022
Oxygen saturation as a predictor of inflammation in obstructive sleep apnea.
Article in Sleep & breathing = Schlaf & Atmung, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Exposure to environmental toxicants and obstructive sleep apnea: a cross-sectional study.Future science OA · 2026Article
- Development and validation of a diagnostic model for obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2026Article
- Intermittent hypoxia aggravates asthma inflammation via NLRP3/IL-1β-dependent pyroptosis mediated by HIF-1α signalling pathway.Chinese medical journal · 2025Article
- Exploring Exercise Interventions for Obstructive Sleep Apnea: A Scoping Review.Journal of functional morphology and kinesiology · 2025Review
- Upper airway and hyoid bone-related morphological parameters associated with the apnea-hypopnea index and lowest nocturnal oxygen saturation: a cephalometric analysis.BMC oral health · 2025Article
- The Association Between Craniofacial Morphological Parameters and the Severity of Obstructive Sleep Apnea: A Multivariate Analysis Using the Apnea-Hypopnea Index and Nocturnal Oxygen Desaturation.Healthcare (Basel, Switzerland) · 2025Article
- Sleep Disordered Breathing and Neurocognitive Disorders.Journal of clinical medicine · 2024Review
- APPCNS neuroscience & therapeutics · 2023Article
- Evaluation of Inflammation and Oxidative Stress Markers in Patients with Obstructive Sleep Apnea (OSA).Journal of clinical medicine · 2023Article
- [Current Status of and Progress in Research on Obstructive Sleep Apnea and Comorbid Depressive Disorders].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2023Review
- "Leaky Gut" as a Keystone of the Connection between Depression and Obstructive Sleep Apnea Syndrome? A Rationale and Study Design.Metabolites · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeObstructive sleep apnea (OSA) is a chronic sleep disorder, and its prevalence is increasing worldwide. This disorder has been consistently associated with several comorbidities. Although it is clear that obstructive sleep apnea severity is associated with inflammation, the trigger for this phenomenon continues to puzzle scientists. Here, we investigated the relationship between obstructive sleep apnea severity and immune parameters.
methodsIn this cross-sectional epidemiological research, we analyzed the immune profile of 461 adults according to OSA severity (mild, moderate, and severe) and oxygen saturation.
resultsThe hallmark of OSA severity - the apnea-hypopnea index (AHI) - weakly correlated with an inflammatory profile. However, individuals who experienced lower oxygen saturation were more likely to exhibit higher total leukocyte and neutrophil counts, a higher neutrophil-lymphocyte ratio (NLR), and an increased concentration of C-reactive protein.
conclusionOur findings indicated that oxygen saturation is a predictor of inflammation during OSA and should be considered crucial in disease diagnostic and treatment strategies.
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