Evidence map›Paper›PMID 34792683›Full record

ArticleClinical autonomic research : official journal of the Clinical Autonomic Research Society2022

Do meals affect heart rate and symptoms in postural orthostatic tachycardia syndrome?

Kate M Bourne, Lauren E Stiles, Satish R Raj, Cyndya A Shibao

Registry-linked trialOpen access · greenAbstract readLetter
In one paragraph

Article in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05375968 (Mechanism of Glucose-dependent Insulinotropic Polypeptide), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05375968 phase2recruitingnot on this mapstarted 2023, after this paper: background citation

Mechanism of Glucose-dependent Insulinotropic Polypeptide (GIP) on Splanchnic Venous Capacitance in Postural Tachycardia Syndrome

TypeinterventionalSponsorVanderbilt University Medical CenterRan2023 to 2028Enrolled50ConditionsPostural Tachycardia Syndrome (POTS)ArmsMeasurement of Splanchnic venous capacitance(SVC)done at Baseline and after 90 min of 75 g glucose in Healthy Controls POTS patients, Measurement of Splanchnic venous capacitance(SVC)done at Baseline and after 90 min of 75 g glucose in Healthy Controls, Compare change is SVC and SMA flow due to GIP antagonist GIP(3-30)NH2, Compare change is SVC and SMA flow due to saline
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Kate M BourneDepartment of Cardiac Sciences, Cumming School of Medicine, Libin Cardiovascular Institute, University of Calgary, Calgary, AB, Canada.ORCID 0000-0002-8355-0002
Lauren E StilesDepartment of Neurology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA.
Satish R RajDepartment of Cardiac Sciences, Cumming School of Medicine, Libin Cardiovascular Institute, University of Calgary, Calgary, AB, Canada.ORCID 0000-0002-5890-3785
Cyndya A ShibaoDivision of Clinical Pharmacology, Department of Medicine, Vanderbilt Autonomic Dysfunction Center, Vanderbilt University Medical Center, Nashville, TN, USA. Cyndya.shibao@vumc.org.ORCID 0000-0002-4518-6801
University of Calgary · CAStony Brook School · USVanderbilt University Medical Center · US

Funding

Structural genomics of norepinephrine transportersP01HL056693 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DIEDRICH, ANDRE · 1997 to 2016
$30.8M
Mechanism of Glucose-dependent insulinotropic polypeptide (GIP) on Splanchnic Venous Capacitance in Postural Tachycardia SyndromeR01HL159203 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Cyndya Adriana Shibao · 2022 to 2026
$4.1M
Enhancing parasympathetic activity to reduce vascular oxidative stress and endothelial dysfunctionR01HL157584 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KIRABO, ANNET, SHIBAO, CYNDYA ADRIANA · 2021 to 2024
$3.0M
The Vanderbilt Institute for Clinical and Translational Research (VICTR) KL2KL2RR024977 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$3.0M
FDA HHS R01 FD004778NCRR NIH HHS KL2 RR024977NHLBI NIH HHS P01 HL056693NHLBI NIH HHS R01 HL157584NHLBI NIH HHS R01 HL159203
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Postural Orthostatic Tachycardia SyndromeHeart RateHumansMealsTilt-Table Test

Identifiers

PMID34792683
PMCPMC11107475
OpenAlexW3211880341

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.