ArticleJournal of magnetic resonance imaging : JMRI2022
Non-Invasive Assessment of Damping of Blood Flow Velocity Pulsatility in Cerebral Arteries With MRI.
Article in Journal of magnetic resonance imaging : JMRI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 28 citations in OpenAlex.
- Regional cerebral arterial elasticity is associated with cardiovascular health in cognitively healthy older adults.bioRxiv : the preprint server for biology · 2026Article
- Exploring the Role of Vascular Factors and Tissue Properties in Pulsatile Brain Deformation.NMR in biomedicine · 2026Article
- Sex differences in cerebral pulsatility and damping: A 4D flow MRI study.Experimental physiology · 2026Article
- Intracranial arterial calcification and cerebrovascular function in the general aging population - A 7T MRI Study.Cerebral circulation - cognition and behavior · 2026Article
- A novel early imaging biomarker for glymphatic function: Cerebral cortical arterial pulsatility index from 2-Minute phase-contrast MRI.The journal of prevention of Alzheimer's disease · 2025Article
- Tactile-Transparent Wearable Sensor for Clinician-Friendly Pulse Wave Velocity Monitoring and Cardiovascular Risk Profiling.ACS nano · 2025Article
- Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI.Experimental physiology · 2025Review
- Blood flow in the human cerebral cortex: Large-scale pial vascularization and 1D simulation.PLoS computational biology · 2025Article
- Simultaneous Assessment of Arterial Pulsatility Across Multiple Segments of Cerebral Arteries Using Multiband Dual-VENC Phase-Contrast MRI.NMR in biomedicine · 2025Article
- The Carotid Siphon as a Pulsatility Modulator for Brain Protection: Role of Arterial Calcification Formation.Journal of personalized medicine · 2025Review
- Analysis of the sample size used in clinical MRI studies.PloS one · 2025Article
- In Vivo Deformation of the Human Basilar Artery.Annals of biomedical engineering · 2025Article
- Assessment of arterial pulsatility of cerebral perforating arteries using 7T high-resolution dual-VENC phase-contrast MRI.Magnetic resonance in medicine · 2024Article
- Measuring global cerebrovascular pulsatility transmission using 4D flow MRI.Scientific reports · 2024Article
- Assessment of Small Vessel Function Using 7T MRI in Patients With Sporadic Cerebral Small Vessel Disease: The ZOOM@SVDs Study.Neurology · 2024Observational
- Pulsatility analysis of the circle of Willis.Aging brain · 2024Article
- In vivo detection of penetrating arteriole alterations in cerebral white matter in patients with diabetes with 7 T MRI.Magnetic resonance imaging · 2023Article
- Impaired damping of cerebral blood flow velocity pulsatility is associated with the number of perivascular spaces as measured with 7T MRI.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023Article
- 5-Year Associations among Cerebral Arterial Pulsatility, Perivascular Space Dilation, and White Matter Lesions.Annals of neurology · 2022Article
- Pulsatility Index in the Basal Ganglia Arteries Increases with Age in Elderly with and without Cerebral Small Vessel Disease.AJNR. American journal of neuroradiology · 2022Article
Corrections and comments
- Commented on by
Authors and funding
12 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDamping of heartbeat-induced pressure pulsations occurs in large arteries such as the aorta and extends to the small arteries and microcirculation. Since recently, 7 T MRI enables investigation of damping in the small cerebral arteries. PURPOSE: To investigate flow pulsatility damping between the first segment of the middle cerebral artery (M1) and the small perforating arteries using magnetic resonance imaging. STUDY TYPE: Retrospective. SUBJECTS: Thirty-eight participants (45% female) aged above 50 without history of heart failure, carotid occlusive disease, or cognitive impairment. FIELD STRENGTH/SEQUENCE: 3 T gradient echo (GE) T1-weighted images, spin-echo fluid-attenuated inversion recovery images, GE two-dimensional (2D) phase-contrast, and GE cine steady-state free precession images were acquired. At 7 T, T1-weighted images, GE quantitative-flow, and GE 2D phase-contrast images were acquired. ASSESSMENT: Velocity pulsatilities of the M1 and perforating arteries in the basal ganglia (BG) and semi-oval center (CSO) were measured. We used the damping index between the M1 and perforating arteries as a damping indicator (velocity pulsatility STATISTICAL TESTS: Correlations of LVSV, MAP, PP, and PWV with velocity pulsatility in the M1 and small perforating arteries, and correlations with the damping indices were evaluated with linear regression analyses.
resultsPP and PWV were significantly positively correlated to M1 velocity pulsatility. PWV was significantly negatively correlated to CSO velocity pulsatility, and PP was unrelated to CSO velocity pulsatility (P = 0.28). PP and PWV were uncorrelated to BG velocity pulsatility (P = 0.25; P = 0.68). PWV and PP were significantly positively correlated with the CSO damping index. DATA
conclusionOur study demonstrated a dynamic damping of velocity pulsatility between the M1 and small cerebral perforating arteries in relation to proximal stress. LEVEL OF EVIDENCE: 4 TECHNICAL EFFICACY: Stage 1.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.