Evidence map›Paper›PMID 34791910›Full record

ReviewDiabetes & vascular disease research

Early detection of diabetic nephropathy in patient with type 2 diabetes mellitus: A review of the literature.

Sopida Thipsawat

Registry-linked trialOpen access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Diabetes & vascular disease research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06563791 (Assessment of the Association Between Visceral Obesity and the Progression of Diabetic Nephropathy), which is not on this map. Cited by 150 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
150citing papers in PubMed, 7 pooled it
20.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06563791 not yet recruitingnot on this map

Assessment of the Association Between Visceral Obesity and the Progression of Diabetic Nephropathy

TypeobservationalSponsorAssiut UniversityRan2024 to 2025Enrolled100ConditionsDiabetic Nephropathies
3 · Its place in the literature

Who cites it

150 citing papers in PubMed, 7 syntheses or guidelines pooled it, 273 citations in OpenAlex.

  1. Pooled it
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  9. The Role of the Notch1 Signaling Pathway in the Pathogenesis and Treatment of Diabetic Foot: A Review.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026
    Review
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  11. Foods (Basel, Switzerland) · 2026
    Article
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90 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Sopida ThipsawatSchool of Nursing, 65133Walailak University, Thai Buri, Thailand.ORCID 0000-0002-7666-7384
Walailak University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type 2 diabetes mellitus is a pathology of heterogeneous etiology characterized by hyperglycemia resulting from lack of insulin action, insulin secretion, or both, and the population with diabetes mellitus is predicted to be about 439 million worldwide by 2030. Prolong diabetes has been related with microvascular complications especially diabetic nephropathy. DN is the most common complication of type 2 diabetes mellitus, and it is the leading cause of end-stage renal disease worldwide. It is crucial to diagnose patients who are more sensible to develop DN for better control of the process of disease. Several factors and mechanisms contribute to the development and outcome of diabetic nephropathy. Microalbuminuria is an early marker of DN and use it as a routine for screening, but the renal damages may be happening even without microalbuminuria. There are several significant kidney damage and disease biomarkers which helps in early detection of DN. An early biomarker may allow earlier diagnosis, treatment reduces DN prevalence and slows DN progression. Therefore, this review focuses on laboratory biomarkers that are earlier, more validation of an early and specific biomarker could potentially make it possible for early diagnosis, treatment, and retardation of progression of diabetic nephropathy.

Indexed as

Diabetes Mellitus, Type 2Diabetic NephropathiesAlbuminuriaBiomarkersEarly DiagnosisHumansBiomarkersbiomarkerdiabetes kidney diseasediabetic nephropathyEarly detectionearly diagnosistype 2 diabetes mellitus

Identifiers

PMID34791910
PMCPMC8606936
OpenAlexW3213836033

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.